张天富 办公室:二期科技大楼645
职称:副教授 专业技术职务:副高 导师资格:学术&专业型硕导 已培养硕士生人数:2 招生专业:生物医学工程、药学 电子邮件:zhangtf@gzhmu.edu.cn 单位:广州医科大学生物医学工程学院 研究方向 |
1. 具有AIE性质的多功能荧光探针的设计与开发 2. 多功能纳米/高分子材料在免疫调控方面的 3. 以光疗为基础,开发光疗/免疫治疗/新型疗法等联合治疗体系
教育经历(按时间正序,格式参考如下) | 2013.09—2015.06 | 中山大学, 化学 | 学士 | 2015.09—2017.06 | 香港理工大学, 化学科技 | 学士 | 2017.09—2021.07 | 香港科技大学 | 博士 |
工作经历(按时间正序,格式参考如下) | 2021.08—2022.08 | 香港心脑血管健康工程中心 | 博士后 | 2022.08—2023.01 | 香港心脑血管健康工程中心 | 副研究科学家 |
学术任职兼职(格式参考如下) | 任职机构 | 具体任职 | 年限 | 1. Interdisciplinary Medicine期刊 | 青年编委 | 2023.10-2025.10 |
主持市级及以上科研/教学项目(仅限近五年主持的项目,即项目结束时间在2019.01之后的,包括项目类别,名称、编号、经费、期限,格式参考如下) | 2024-01-01 至2026-12-31 | 国家自然科学基金-青年科学基金项目 30万元 在研 | 基于近红外两性荧光材料的自组装调控光诊疗性能用于增强抗肿瘤免疫研究(52303224) | 2024-01-01 至2026-12-31 | 广东省自然科学基金-面上项目 15万元 在研 | 离子型荧光材料的构建及NIR成像介导的聚集体光疗-免疫联合癌症治疗研究 |
主讲课程(格式参考如下) | 时间 | 课程名称 | 学时 | 202303-202306 | 纳米生物医学技术(临床专业专选课) | 20 | 202309-202312 | 分子影像学 | 3 | 202009-202312 | 纳米生物医学技术(公选课) | 20 |
近五年代表性科研/教学论文(#:所有第一作者,*:所有通讯作者,≤20篇,格式参考如下) | 1.Tianfu Zhang,# Xing Yang,# Xinwen Ou,# Michelle M. S. Lee, Jianyu Zhang, Changhuo Xu, Xinghua Yu, Ping Gong,* Jacky W. Y. Lam, Pengfei Zhang,* Ben Zhong Tang* Tailoring Amphiphilic Structure of Zwitterionic AIE Photosensitizers to Boost Antitumor Immunity. Adv. Mater. 2023, 35, 2303186. (论文,中科院材料一区,IF = 29.4) 2.Tianfu Zhang,# Jianyu Zhang,# Fu-Bing Wang, Hui Cao, Daoming Zhu, Xiaoyu Chen, Changhuo Xu, Xueqin Yang, Wenbin Huang, Zhaoyu Wang, Jiefei Wang, Zikai He, Zheng Zheng,* Jacky Wing Yip Lam,* Ben Zhong Tang* Mitochondria-Targeting Phototheranostics by Aggregation-Induced NIR-II Emission Luminogens: Modulating Intramolecular Motion by Electron Acceptor Engineering for Multi-Modal Synergistic Therapy. Adv. Funct. Mater. 2022, 32, 2110526. (论文,中科院材料一区,IF= 19.9) 3.Tianfu Zhang,# Yuanyuan Li,# Zheng Zheng, Ruquan Ye, Yiru Zhang, Ryan T.K. Kwok, Jacky W. Y. Lam and Ben Zhong Tang*. In Situ Monitoring Apoptosis Process by a Self-Reporting Photosensitizer. J. Am. Chem. Soc. 2019, 141, 5612. (论文,中科院化学一区,IF= 16.8) 4.Tianfu Zhang,# Xiaoyu Chen,# Congmin Yuan,# Xiaobin Pang, Ping Shangguan, Lulu Han, Yisheng Liu, Jianwei Sun, Jacky W. Y. Lam, Jiefei Wang,* Bingyang Shi,* Ben Zhong Tang* Near‐Infrared Aggregation‐Induced Emission Luminogens for In Vivo Theranostics of Alzheimer’s Disease. Angew. Chem. Int. Ed. 2023, 62, e202211550. (论文,中科院化学一区,IF= 16.8) 5.Tianfu Zhang,*# Yanlin Deng,# Sylvia Yang Liu,# Song Lin Chua,* Ben Zhong Tang,* Bee Luan Khoo* Bacterial Targeted Photosensitizers with Aggregation-induced Emission Property Synergistically Promote Chemotherapy for the Treatment of Inflammatory Cancer. Chem. Eng. J 2022, 447, 137579. (论文,中科院化学一区,IF= 14.6) 6.Tianfu Zhang,# Zeming Liu,# Wenxue Tang,# Meng Lyu, Jacky Wing Yip Lam, Qinqin Huang,* Ben Zhong Tang* Mitochondria-Targeting Type I AIE Photosensitizer Combined with H2S Therapy: Uninterrupted Hydroxyl Radical Generation for Enhancing Tumor Therapy. Nano Today 2022. 46, 101620. (论文,中科院化学一区,IF= 20.7) | 7.Tianfu Zhang,*# You Pan,# Meng Suo,# Meng Lyu, Jacky Wing Yip Lam, Zhaokui Jin,* Shipeng Ning,* Ben Zhong Tang* Photothermal-Triggered Sulfur Oxide Gas Therapy Augments Type I Photodynamic Therapy for Potentiating Cancer Stem Cell Ablation and Inhibiting Radioresistant Tumor Recurrence Adv. Sci. 2023, 2304042. (论文,中科院化学一区,IF= 17.5) | 8.You Pan,# Qinqin Huang,# Meng Suo,# Meng Lyu, Yi Jiang, Shile, Wang, Wenxue Tang, Shipeng Ning,* Tianfu Zhang* Near-infrared laser-activated aggregation-induced emission nanoparticles boost tumor carbonyl stress and cancer immunotherapy Aggregate, 2023, e432. (论文,IF= 18.8) | 9.Shipeng Ning,# Xing Zhang, #Meng Suo,# Meng Lyu, You Pan, Yi Jiang, Huawei Yang, Jacky Wing Yip Lam, Tianfu Zhang,* Linghui Pan,* Ben Zhong Tang* Platelet-derived exosomes hybrid liposomes facilitate uninterrupted singlet oxygen generation to enhance breast cancer immunotherapy. Cell Rep. Phys. Sci. 2023, 4, 101505. (论文,中科院生物一区,IF= 8.9) 10.Shipeng Ning,# Meng Lyu,# Daoming Zhu,# Jacky W. Y. Lam, Qinqin Huang,* Tianfu Zhang,* Ben Zhong Tang* Type-I AIE Photosensitizer Loaded Biomimetic System Boosting Cuproptosis to Inhibit Breast Cancer Metastasis and Rechallenge. ACS Nano, 2023, 17, 10206. (论文,中科院材料一区,IF= 18) 11.Shipeng Ning,# Meng Suo,# Qinghua Huang,# Song Gao, Kun Qiao, Meng Lyu, Qinqin Huang,* Tianfu Zhang,* Ben Zhong Tang* Biomimetic fusion liposomes boosting antitumor immunity and promote memory T cell differentiation to inhibit postoperative recurrence of breast cancer. Nano Today, 2024, 54, 102106. (论文,中科院材料一区,IF= 18.0) | 授权专利(要有至少3列,包括时间、专利名称、专利发明人、授权编号) | | 20240315 | 一种新型的闪光放疗复发抑制剂 | 张天富,宁峙彭,唐本忠,索萌 | 202410298718.7 | | 20240206 | 一种新型的闪光放疗增敏剂 | 张天富,宁峙彭,唐本忠,索萌 | 202410166940.1 | | 20211129 | COMPOSITION AND A METHOD FOR DIAGNOSING AND TREATING BACTERLAL INFECTION | Bee Luan Khoo, Tianfu Zhang | 17/536,193 | | 20230506 | 用于对β-淀粉样蛋白成像和抑制β-淀粉样蛋白聚集的探针 | 唐本忠,张天富,林荣业 | 202211323635.6 | |
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