【个人简介】

叶裕丰，男，硕士研究生，主任医师，广州中医药大学博士研究生导师，广州医科大学、华南师范大学、深圳大学硕士研究生导师，医院重点培养的“百人计划”骨干。现担任番禺区医学影像研究所副所长，广东省医学会人工智能分会委员、广东省医疗行业协会影像管理分会委员，广东省医学会放射分会青年委员等。

教育经历：

1.2014/09-2020/07，暨南大学，第一临床医学院，硕士研究

2.2001/09-2006/06，广州医科大学，医学影像系，学士

科研与学术工作经历：

1.2021/01-至今 广州医科大学附属番禺区中心医院 主任医师，番禺区医学影像研究所副所长

2.2019/08-2020/02，香港中文大学（威尔斯亲王医院），访问学者

3.2019/01-2020/12，广州市番禺区中心医院副主任医师，番禺区医学影像研究所秘书

4.2017/10-2018/03，广州市番禺区中心医院，番禺区医学影像研究所秘书，中山大学孙逸仙医院进修CT/MR诊断

5.2016/01-2020/12，广州市番禺区中心医院，放射科，副主任医师

6.2012/06-2015/12，广州市番禺区中心医院，放射科，主治医师

7.2006/07-2012/05，广州市番禺区中心医院，放射科，住院医师

【研究方向】

鼻咽癌和下肢深静脉血栓的磁共振成像研究和人工智能分析

【科研项目】

1. 广东省医学会临床科研基金，2024QC-B1011,基于BTI技术对冠心宁片联合利伐沙班治疗下肢深静脉血栓的疗效评价,2025/04-2027/04,5万，在研，主持

2. 番禺区科技工业商务和信息化局，2021-Z04-001，基于鼻咽癌多模态影像的靶区勾画和疗效预测一体化智能系统开发，2022/01-2024/12，20万，结题，主持

3. 广州市卫生健康委员会，20211A011117，基于多模态影像人工智能分析预测鼻咽癌放化疗后疗效的研究，2021/04-2023/03，1.5万，结题，主持

4. 广州市番禺区科技工业商务和信息化局，2020-Z04-048，重金属与挥发性有机物联合暴露对环卫工人肺功能影响的研究，2021/01-2023/12，1.0万，结题，主持

5. 国家自然科学基金，81874276，基于出生队列的孕期细颗粒物暴露与婴幼儿哮喘的暴露-反应关系及表观遗传机制研究，2019/01-2022/12，58万（获5万元合作经费），结题，第二负责人（合作单位负责人）。

6. 广东省科技厅科技计划立项，2017ZC0374，磁共振氨基质子转移成像新技术在鉴别鼻咽癌放化疗后局部复发的研究，2017/07-2020/06，自筹10万，主持，已结题。本项目同时获得广州市番禺区工商信局医疗卫生重点项目，2017-Z04-08，2017/01-2019/12，资助10万元，已结题，主持。

7. 广州市科技计划项目，201804010111，磁共振氨基质子转移成像识别鼻咽癌放化疗后局部复发的技术原理研究, 2018/04 -2021/03，20万，已结题，主持。

8. 广东省教育厅教学改革研究项目，2015JDB088，基于PACS系统构建医学影像教学数据库及多元化教学模式的探索，2016/01-2017/12，自筹1万元，已结题，主持。

9. 广州市番禺区科技和信息化局科技计划医疗领域的重大项目，2013-Z03-01，MR灌注成像在局部晚期宫颈癌化疗疗效评价的研究，2013/10-2015/09,2万元，已结题，主持。

【代表性论文及著作】

(1) Leizi Li, Jingchun Yu , Yijin Li, Jinbo Wei , Ruifang Fan , Dieen Wu* and Yufeng Ye*.Multi-sequence generative adversarial network: better generation for enhanced magnetic resonance imaging images[J].Frontiers in Computational Neuroscience.2024,Volume 18:1365238. doi: 10.3389/fncom.2024.1365238

(2) Yufeng Ye,Naiwen Zhang, Dasheng Wu, Bingsheng Huang, Xun Cai,Xiaolei Ruan,5 Liangliang Chen,Kun Huang,Zi-Ping Li,Po-Man Wu, Jinzhao Jiang, Guo Dan* , Zhenpeng Peng*.Deep Learning Combined with Radiologist’s Intervention Achieves Accurate Segmentation of Hepatocellular Carcinoma in Dual-Phase Magnetic Resonance Images[J].BioMed Research International Volume 2024, Article ID 9267554, 13 pages https://doi.org/10.1155/ 2024/9267554

(3) Jiabin Liang#, Jie Feng#, Zhijie Lin#, Jinbo Wei, Xun Luo, Qing Mei Wang,Bingjie He,Hanwei Chen*,Yufeng Ye*. Research on prognostic risk assessment model for acute ischemic stroke based on imaging and multidimensional data[J].Frontiers in Neurology, 2023, 14: 1-11

(4) Yong Jiang# , Shuxin Zhong#, Shenghua He # , Juanling Weng , Lijin Liu , Yufeng Ye* and Hanwei Chen* . Biomarkers (mRNAs and non-coding RNAs) for the diagnosis and prognosis of rheumatoid arthritis[J].Frontiers in Immunology(2023). 14:1087925. doi: 10.3389/fimmu.2023.1087925

(5) Zhilin Li, Hongxuan Kuang, Leizi Li, Maorong Wu ,Zengquan Liao, Keqin Zeng, Yufeng Ye*,Ruifang Fan.What adverse health efects will environmental heavy metal coexposure bring us: based on a biological monitoring study of sanitation workers[J]. Environmental Science and Pollution Research, (2022).https:// doi.org/10.1007/s11356-022-24805-9

(6) Zhu Sui#,Chen Guimin#,Ye Yufeng#,Zhou He,He Guanhao,Chen Hanwei,Xiao Jianpeng,Hu Jianxiong,Zeng Fangfang,Yang Pan,Liu Chaoqun,He Zhongrong,Wang Jiong,Cao Ganxiang,Chen Yumeng,Feng Hao,Ma Wenjun,Liu Tao*.Effect of maternal ozone exposure before and during pregnancy on wheezing risk in offspring: A birth cohort study in Guangzhou, China[J]. Environmental Research,2022,212(PC). doi.org/10.1016/j.envres. 2022.113426

(7) Haoyu Zhang , Huizhong Jiang, Mengya Zhao, Yan Xu ,Jiabin Liang , Yufeng Ye* , and Hanwei Chen*.Treatment of Gout with TCM Using Turmeric and Corn Silk: A Concise Review Article and Pharmacology Network Analysis[J]. Evidence-Based Complementary and Alternative Medicine,2022,2022(2022). doi.org/10.1155/2022/ 3143733

(8) Bin Huang#, Yufeng Ye#, Ziyue Xu, Zongyou Cai, Yan He, Zhangnan Zhong, Lingxiang Liu, Xin Chen, Hanwei Chen*, and Bingsheng Huang*. 3D Lightweight Network for Simultaneous Registration and Segmentation of Organs-at-Risk in CT Images of Head and Neck Cancer. IEEE Transactions on Medical Imaging.vol. 41, no. 4, pp. 951-964, April 2022, .DOI 10.1109/TMI. 2021.3128408,（因子11.037）

(9) Moran Dong#, Rui Qian#, Jiaqi Wang#, Jingjie Fan#, Yufeng Ye#, He Zhou , Brian Win , Eve Reid , Suijin Zheng , Yanyun Lv , Yudong Pu, Hanwei Chen , Juan Jin , Qingmei Lin, Xiaoyang Luo, Guimin Chen , Yumeng Chen , Zhongrong He, Guanhao He , Shouzhen Cheng, Jianxiong Hu , Jianpeng Xiao , Wenjun Ma, Tao Liu* and Xiaozhong Wen.Associations of COVID-19 lockdown with gestational length and preterm birth in China[J]. BMC Pregnancy and Childbirth (2021) 21:795 .doi.org/10.1186/s12884-021-04268-5

(10) Yufeng Ye#, Jian Zhang, Bingsheng Huang, Xun Cai, Panying Wang,Ping Zeng, Songxiong Wu, Jinting Ma, Han Huang, Heng Liu, Guo Dan* and Guangyao Wu*. Characterizing the Structural Pattern of Heavy Smokers Using Multivoxel Pattern Analysis[J]. Frontiers in Psychiatry, 2021, 11:607003.doi: 10.3389/fpsyt.2020.607003

(11) Yufeng Ye#, Zongyou Cai#, Bin Huang, Yan He, Ping Zeng, Guorong Zou, Wei Deng, Hanwei Chen*and Bingsheng Huang*. Fully-Automated Segmentation of Nasopharyngeal Carcinoma on Dual-Sequence MRI Using Convolutional Neural Networks. Frontiers in Oncology.2020, 10(166): 1-12. doi: 10.3389/fonc. 2020.00166

(12) Yufeng Ye#,Xueping He, Chen Huang,Caiyun Shi, Wei Deng, Wenfeng Luo,Jianke Liang, Zhuonan He, Huan Mao, Qiwei Liang, Dongya Chen, Hanwei Chen* and Guoxi Xie*.Comparison Between the Diagnostic Performance of 1.5 T and 3.0 T field Strengths for Detecting Deep Vein Thrombosis Using Magnetic Resonance Black-Blood Thrombus Imaging.[J].Clin Appl Thromb /Hemost. 2020,26():1076029620921235

(13) Xin Liu#, Yufeng Ye#, Yi Chen, Xiaona Li, Baixiang Feng, Ganxiang Cao, Jianpeng Xiao, Weilin Zeng, Xing Li, Jiufeng Sun, Dan Ning, Yi Yang, Zhenjiang Yao, Yuming Guo, Qiong Wang, Yonghui Zhang, Wenjun Maa, Qingfeng Duh, Bo Zhang, Tao Liu,⁎Effects of prenatal exposure to air particulate matter on the risk of preterm birth and roles of maternal and cord blood LINE-1 methylation: A birth cohort study in Guangzhou, China, Environment International, 133 (2019) 105177.doi.org/10.1016/j.envint. 2019.105177

(14) Qiaoliang Li#, Yuzhen Xu# , Zhewei Chen ,Dexiang Liu , Shiting Feng ,Martin Law , Yufeng Ye* , Bingsheng Huang* Tumor Segmentation in Contrast- Enhanced Magnetic Resonance Imaging for Nasopharyngeal Carcinoma: Deep Learning with Convolutional Neural NetworkBioMed Research International, BioMed Research International,Volume 2018, Article ID 9128527, 7 pages.doi.org/10.1155/2018/9128527

(15) Liangliang Chen^#, Yufeng Ye^#, Hanwei Chen^#, Shihui Chen, Jinzhao Jiang, Guo Dan1*,Bingsheng Huang*,Dynamic Contrast-enhanced Magnetic Resonance Imaging for Differentiating Between Primary Tumor, Metastatic Node and Normal Tissue in Head and Neck Cancer,Current Medical Imaging , 2018, 14(3), 416-421

【所获荣誉和奖励】

1.2021-2023年荣获广州市番禺区中心医院“优秀研究生导师”。