余梅，博士，广州市妇女儿童医疗中心副主任医师，广东省健康管理协会口腔颌面头颈医学专业委员会委员

一直从事口腔颌面部肿瘤及数字化口腔诊疗相关的教学与科研工作，第一/通讯作者发表专业论文20余篇，其中 SCl收录5篇。

联系邮箱：meiyuss119@163.com

研究方向：

1. 口腔颌面部肿瘤靶向治疗

2. 数字化口腔诊疗

主要科研项目

1.基于新型细胞穿膜肽和pH响应性腙键构建靶向实体瘤的触发释药系统。广州市科技计划项目，起止日期：2021.04.01-2023.03.31）；项目编号：202102010270

代表论文及著作

(1) Mei Yu, Xiaolong Li, Xiaofeng Huang, Jing Zhang, Yan Zhang, Hua

Wang*. New cell penetrating peptide (KRP) with multiple physicochemical properties endows doxorubicin with tumor targeting and improves its therapeutic index. ACS Applied Materials & Interfaces, 2019, 11 (2): 2448–2458.（ISSN: 1944-8244；IF：10.383）

(2) Mei Yu#, Xiaolong Li#, Rui Liang, Jing Yang, Yan Zhang, Hua Wang*. A new ligand of CD105 screened out by phage display technology provides a reliable identification of recurrent or metastasizing pleomorphic adenoma from pleomorphic adenoma. International Immunopharmacology, 2018,65: 37–43.（ISSN: 1567-5769；IF：5.174）.

(3) Mei Yu#, *, Guiyun Wu#, Yiyang Chen, Hongtao Wang, Yongbo Gao, Anxun Wang*. Bioinformatic screening and experimental analysis identify SFRP1 as a prognostic biomarker for tongue squamous cell carcinomas. Archives of Oral Biology, 110 (2020) 104587. (ISSN: 0003-9969; IF:2.633).  

(4) Mei Yu#, *, Limin Xiao#, Yiyang Chen, Hongtao Wang, Yongbo Gao, Anxun Wang*. Identification of a potential target for treatment of squamous cell carcinoma of the tongue: follistatin. British Journal of Oral & Maxillofacial Surgery，2020，58：437-442. (ISSN 0266-4356; IF:2.018)

(5) Jing Zhang, Mei Yu, Xiaolong Li, Xiaofeng Huang, and Hua Wang*. Combination therapy improves immune response and prognosis in patients with advanced oral mucosal melanoma: a clinical treatment success. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. doi: 10.1016/j.oooo.2018.05.004. （ISSN: 2212-4403；IF：1.601）