【个人简介】

刘志平，广州医科大学附属第二医院眼科主任医师、副教授、硕士生导师、住培导师、本科生导师、广州医科大学南山班导师、广州医科大学创新班导师、广州医科大学全英教师，中山大学中山眼科中心眼科学博士，第二届广东省实力中青年医师，美国巴斯康帕默眼科研究所（Bascom Palmer Eye Institute）博士后，广州市高层次卫生人才医学骨干人才，广州市高层次人才青年后备人才，广州医科大学高水平大学建设学术骨干人才，广州医科大学“南山学者”后备人才，广州市卫生健康委员会优秀人才。美国眼科学会青年会员，美国视觉与眼科协会会员，广东省高校科技成果转化中心特聘专家，广东省科技厅评审专家，广东省医院协会眼病防治管理专业委员会常务委员，广东省医学会眼科学分会委员，广州市医学会眼科学分会委员兼秘书，广东省医疗行业协会眼科管理分会委员，广东省眼健康协会防盲治盲专业委员会、眼整形与美容专业委员会委员，广东省精准医学应用学会眼前段疾病分会委员，广东省预防医学会眼科疾病防治专业委员会委员，中国人口促进会眼科专业委员会角膜与眼表疾病分会委员，中国医药教育协会数字影像与智能医疗专委会委员，广州市医师协会眼整形眼眶病医师分会委员。担任多家高水平杂志的编委或审稿专家，如《中国组织工程研究》杂志青年编委，《British Journal of Ophthalmology》、《Survey of Ophthalmology》、《International Journal of Ophthalmology》、《Annals of Eye Science》、《Cellular & Molecular Biology Letters》、《Biopha》、《Frontiers in Medicine》、《Journal of Clinical Medicine》、《Diagnostics》、《International Journal of Molecular Science》、《International Journal of Ophthalmology & Visual Science》、《Medical Sciences》、《Medicina》等杂志审稿专家。

【研究方向】

角膜眼表疾病；视网膜血管性疾病；眼科人工智能

【科研项目】

1. 广州市科学技术局，市校联合项目，2024A03J0207，无载体组织工程角膜内皮细胞片构建及其体内转归与功能评价，2024-01-01至2025-12-31,23万元，立项，主持。

2. 广东省基础与应用基础研究委员会，2020A1515010276，circBIRC6/ ESRP1介导的miR-31对角膜缘干细胞微环境稳态的调控机制，2019-10至2022-09，10万元，在研，主持。

3. 广州市科技创新委员会，一般项目，201804010038，LncRNA-ANCR/miR-31与Wnt3a信号通路调控角膜缘干细胞动态平衡的机制研究，2018-04至2021-03，20万元，已结题，主持。

4. 广州市教育局，市属高校”羊城学者“青年科研骨干培养项目，1201581612，应用羊膜微环境重建大鼠干眼模型正常眼表的机制研究，2015-10至2018-09，15万元，结题，主持。

5. 广东省科技厅，自由申请项目， 2014A030313487，microRNAs调控角膜缘干细胞自我更新和分化的实验研究，2015-01至2018-01，10万元，已结题，主持。

6. 国家自然科学基金委员会，青年项目，81300732，miR-31/p21 相关信号通路调控角膜缘干细胞生物学特性的机制研究，2014/01-2016/12，23万元，已结题，主持。

【代表性论文及著作】

1. Zhuang J, Li F, Liu X, Liu Z, Lin J, Ge Y, Kaminski J.M, Summers J.B, Wang Z, Ge J, Yu K. Lithium chloride protects retinal neurocytes from nutrient deprivation by promoting DNA non-homologous end-joining. Biochem Biophys Res Commun, 2009, 380(3): 650-654.

2. Liu Y, Ding Y, Ma P, Wu Z, Duan H, Liu Z, Wan P, Lu X, Xiang P, Ge J, Wang Z. Enhancement of long-term proliferative capacity of rabbit corneal epithelial cells by embryonic stem cell conditioned medium. Tissue Eng Part C Methods, 2010,16(4): 793-802.

3. Lu X, Chen D, Liu Z, Li C, Liu Y, Zhou J, Wan P, Mou Y.G., Wang Z. Enhanced survival in vitro of human corneal endothelial cells using mouse embryonic stem cell conditioned medium. Mol Vis, 2010,16: 611-622.

4. Zhan W, Liu Z, Liu Y, KeQ, Ding Y, Lu X, Wang Z. Modulation of rabbit corneal epithelial cells fate using embryonic stem cell extract. Mol Vis, 2010, 16: 1154-1161.

5. Liang X, Lin Y, Wang Z, Lin L, Zeng S, Liu Z, Li N, Liu Y. A modified bicanalicular intubation procedure to repair canalicular lacerations using silicone tubes. Eye (Lond), 2012,26(12): 1542-1547.

6. Liang X, Liu Z, Lin Y, Li N, Huang M, Wang Z. A modified symblepharon ring for sutureless amniotic membrane patch to treat acute ocular surface burns. J Burn Care Res, 2012,33(2): e32-8.

7. Liu Z, Zhuang J, Li C, Wan P, Li N, Zhou Q, Zhou C, Huang Z, Wang Z. Long-term cultivation of human corneal endothelial cells by telomerase expression. Exp Eye Res, 2012,100: 40-51.

8. Liang X, Liu Z (Co-first author), Li F, Liu J, Lin L, Li N, Zhong L, Huang D, Wang Z. A novel modified soft probe for identifying the distal cut end in single canalicular laceration. Br J Ophthalmol, 2013,97(5):665-666.

9. Liu Z, Wan P, Duan H, Zhou J, Tan B, Liu Y, Zhou Q, Zhou C, Huang Z, Tian B, Li C, Wang Z. ES Micro-Environment Enhances Stemness and Inhibits Apoptosis in Human Limbal Stem Cells via the Maintenance of Telomerase Activity. PLoS One, 2013,8(1): e53576.

10. Sha X, Liu Z (Co-first author), Song Li, Wang Z, Liang X. Human amniotic epithelial cell niche enhances the functional properties of human corneal endothelial cells via inhibiting P53-survivin-mitochondria axis. Experimental Eye Research, 2013,116:36-46.

11. Liu Z(Corresponding author), Sha X, Liang X, Wang Z. Use of silicone tubes to repair canalicular lacerations via a novel method. Eye Science. 2013, 28(4):195-200.

12. Yang R, Lai H, Sha X, Chen S, Tan Y, Chen W, Liu Z. Relationship between Foxp3-3279(rs376158) Polymorphism and dust mite allergic conjunctivitis. Eye Science,2014,29(4):151-154.

13. Liu Z(Corresponding author), Sha X, Liang X, Wang Z, Liu J. Huang D. Toric intraocular lens vs. peripheral corneal incisions to correct astigmatism in eyes undergoing cataract surgery. Eye Science, 2014, 29(4): 198-203.

14. Sha X, Wen Y, Liu Z, Song L, Peng J, Xie L. Inhibition of α-smooth muscle action expression and migration of pterygium fibroblasts by coculture with amniotic mesenchymal stem cells. Current Eye Research, 2014,39(11):1081-1089.

15. Liu Z(Corresponding author), Zhan W, Zeng M, Chen J, Zou H, Min Z. Enhanced functional properties of human limbal stem cells by inhibition of the miR-31/FIH-1/P21 axis. Acta ophthalmologica, 2017, 95(6): e495-e502.

16. Liu Z, Wang H, Jiang H, Gameiro G, Wang J. Quantitative analysis of conjunctival microvasculature imaged using optical coherence tomography angiography. Eye and Vision, 2019, 6(5):1-9.

17. Liu J, Tonk R, Huang A, Han E, Karp C, Zeng M, Zou H, Zheng Y, Sha X, Liu Z(Corresponding author). Transient effect of suction on the retinal neurovasculature in myopic patients after small-incision lenticule extraction. Journal of Cataract and Refractive Surgery, 2020; 46(2):250–259.

18. Airen S, Shi C, Liu Z, Levin B, Signorile J, Wang J, Jiang H. Focal alteration of the intraretinal layers in neurodegerative disorders. Annals of Eye Science, 2020,5:8.

19. Liu J, Zou H, Zeng M, Huang AM, Chen Y, Han E, Sha X, Liu Z (Corresponding author). Cytoprective effect of amniotic membrane extracts on human corneal epithelial cells exposed to benzalkonium chloride in vitro. Annals of Eye Science, 2020.

20. Shi C, Wang P, Airen S, Brown C, Liu Z, Wang J, Jiang H. Nutritional and medical food therapies for diabetic retinopathy. Eye and Vision,2020,7:33:1-16.

21. Liu Z, Jiang H, Townsend J, Wang J. Improved conjunctival microcirculation in diabetic retinopathy patients with MTHFR polymorphisms after Ocufolin™ Administration. Microvascular Research, 2020,132:104066.

22. Liu Z, Karp CL, Galor A, Bayyat GA, Jiang H, Wang. Role of optical coherence tomography angiography in the characterization of vascular network patterns of ocular surface squamous neoplasia. The Ocular Surface, 2020,18(4):926-935.

23. Liu Z, Jiang H, Townsend J, Wang J. Retinal tissue perfusion reduction best discriminates early stage diabetic retinopathy in patients with type 2 diabetes mellitus. Retina, 2021,41(2):546-554.

24. Liu Z, Wang C, Cai X, Jiang H, Wang J. Discrimination of diabetic retinopathy from optical coherence tomography angiography images using machine learning methods. IEEE ACCESS,2021,9:51689-51694.

25. Liu J, Tonk R, Huang A, Han E, Karp C, Zeng M, Zou H, Zheng Y, Sha X, Liu Z (Corresponding author). Re: Abhijit Sinha Roy: Incorrect assessment of retinal thicknesses after refractive surgery. Journal of Cataract and Refractive Surgery, 2021,47(5):683-684.

26. Liu Z, Jiang H, Townsend J, Wang J. Effects of Ocufolin on retinal microvasculature in patients with mild non-proliferative diabetic retinopathy carrying polymorphisms of the MTHFR gene. BMJ Open Diabetes Research & Care, 2021, 9:e002327.

27. Theotoka  D, Liu Z(Co-first author),  Wall S, Galor A, Bayyat G, Feuer W,  Wang J, Karp C. Optical coherence tomography angiography in the evaluation of vascular patterns of ocular surface squamous neoplasia during topical medical treatment. The Ocular Surface, 2022,25:8-18.

28. Liu Z, Jiang H, Townsend J, Wang J. Improved retinal microcirculation in mild diabetic retinopathy patients carrying MTHFR polymorphisms who received the medical food, Ocufolin®. Clinical Ophthalmology, 2022,16:1497-1504.

29. Jiang H, Liu Z, Townsend J, Wang J. Effects of Methylenetetrahydrofolate Reductase (MTHFR) Polymorphisms on Retinal Tissue Perfusion in Mild Diabetic Retinopathy Patients Receiving the Medical Food, Ocufolin^®. Clinical Ophthalmol, 2023,17:1121-1127.

30. Li H, Liu C, Zhang J, Wang W, Cheng W, Yang R,Huang A, Liang J, Guo J, Liu Z (Corresponding author). The association of homocysteine level with the risk of diabetic nephropathy and diabetic retinopathy in NHANES. Acta Diabetologica,2023,60:907-916.

31. Yu S, Hou Z, Liu Z, Lin Z, Zhong L, Yang Q, Huang W. Belimumab shows promise in neuropsychiatric lupus: Another challenge to find the offender. Rheumatol & Autoimmun. 2023,3(2):115-119.

32. Li H, Yu S, Li P, Zhang J, Maitiyaer M, Huang A, Deng Q, Yang R, Liang J, Huang W, Liu Z (Corresponding author). Microvasculature alterations of peripapillary retina and macula in systemic lupus erythematosus patients without ocular involvement by optical coherence tomography angiography. Retina,2024,44(3):515-526.

33. Li H, Liu C, Huang A,Zhang J, Yang R, Sha X, Liu Z (Corresponding author). Combined central retinal vascular occlusion as the presenting feature in β-thalassemia with iron deficiency anemia. Retin Cases Brief Rep. 2024,18(3):393-395.

34. Li X, Maitiyaer M, Tan Q, Huang W, Liu Y, Liu Z, Wen Y, Zheng Y, Chen X, Chen R, Tao, Yu S. Emerging biologic frontiers for Sjogren’s syndrome: Unveiling novel approaches with emphasis on extra glandular pathology. Front Pharmacol, 2024,15:1377055.

35. Maitiyaer M, Liu Y, Keyimu N, Wen Y, Liu Z, Huang W, Yu S. A novel approach with tofacitinib for the management of keratoderma blennorrhagicum in reactive arthritis: a case report. Front Immunol,2024,15:1399249.

36. Zhang J, Li H, Deng Q, Huang A, Qiu W, Wang L, Xiang Z, Yang R, Liang J, Liu Z (Corresponding author). Correlation between omega-3 intake and the incidence of diabetic retinopathy based on NHANES from 2005 to 2008. Acta Diabetol 2024,61(8):997-1005.

37. Zeng J, Cao X, Chen J, Liu Z, Lyu J, Zhou Q. Assessment of prognostic factors in patients with primary ocular adnexal lymphoma when considering competing risk elements. Clin Exp Ophthalmol.2024. Online ahead of print.

【所获荣誉和奖励】

1. 2013年广东省医学会优秀论文

2. 2014年广州医科大学附属第二医院廉洁文化建设年活动作品鼓励奖

3. 2014年广州医科大学教师授课竞赛（英文授课）优秀奖

4. 2014年可乐必妥眼科病例挑战赛季军

5. 2014年广东省医学会优秀论文

6. 2015年广州医科大学第二临床学院优秀授课（见习带教）老师

7. 2015年广州市医学会先进个人

8. 2016年广州市医学会优秀论文

9. 2016年广州市医学会先进个人

10. 2017年广州市医学会先进个人

11. 2020年广州市医学会优秀论文

12. 2021年广州市医学会先进个人

13. 第二届广东省眼健康科普大赛“举世瞩目”奖（二等奖）

14. 第四届南方健康科普大赛优秀奖（图文奖）

15. 2023年广州市医学会优秀论文（2篇）