刘超,博士,广州市妇女儿童医疗中心优生围产研究所PI。本科毕业于山东大学,2016年于中国科学院动物研究所获得博士学位,同年留所历任助理研究员、副研究员,2018年入选中国科学院青年创新促进会。主要从事蛋白质泛素化和类泛素化修饰在减数分裂、精子形态建成等过程中的调控机制研究,并探索其与男性生殖系统遗传性疾病的关系。迄今已在EMBO J.、Nat. Commun.、Adv. Sci.、Am. J. Hum. Genet.、Autophagy、J. Cell Biol.、Nucleic Acids Res等杂志发表论文40余篇,主持国家自然科学基金面上项目、国家重点研发计划等项目。
联系方式:liuchao@gwcmc.org
代表性文章如下:
1) Liu C#, Liu H#, Zhang H#, Wang L#, Li M, Cai F, Wang X, Wang L, Zhang R, Yang S, Liu W, Liang Y, Wang L, Song X, Su S, Gao H, Jiang J, Li J, Luo M, Gao F, Chen Q, Li W*, Chen ZJ*. Paternal USP26 mutations raise Klinefelter syndrome risk in the offspring of mice and humans. The EMBO journal. 2021 May 12; e106864.
2) Zhang Y#, Liu C#, Wu B, Li L, Li W*, Yuan L*. The missing linker between SUN5 and PMFBP1 in sperm head-tail coupling apparatus. Nat. Commun. 2021 Aug 13;12(1):4926.
3) Liu C#, Zhao HC#, Xiao S#, Han T, Chen Y, Wang T, Ma Y, Gao H, Xie Z, Du L, Li J, Li G*, Li W*. Slx5p-Slx8p promotes accurate chromosome segregation by mediating the degradation of synaptonemal complex components during meiosis. Adv Sci (Weinh). 2020 Jan 1; doi:10.1002/advs.201900739.
4) Zhu F#, Liu C#, Wang F#, Yang X#, Zhang J, Wu H, Zhang Z, He X, Zhang Z, Zhou P, Wei Z, Shang Y, Wang L, Zhang R, Ouyang YC, Sun QY, Cao Y*, Li W*. Mutations in PMFBP1 Cause Acephalic Spermatozoa Syndrome. Am J Hum Genet. 2018 Aug 2;103(2):188-199.
5) Liu C, Liu W, Ye Y, Li W*. Ufd2p synthesizes branched ubiquitin chains to promote the degradation of proteins modified with atypical ubiquitin chains. Nat. Commun. 2017 Feb 6;8:14274.
6) Liu C, Wang HN, Shang YL, Liu WX, Song ZH, Zhao HC, Wang LN, Jia PF, Gao FY, Xu ZL, Yang L, Gao F, Li W*. Autophagy is required for ectoplasmic specialization assembly in Sertoli cells. Autophagy. 2016 May 3;12(5):814-32.