姓 名：马宁，男，回族，研究员，博导，导师类型：学术型，最后学历：博士研究生 最后学位：理学博士

工作单位：广州国家实验室

邮箱：ma_ning@gzlab.ac.cn

个人简介

马宁，广州实验室研究员，本科毕业于中国海洋大学，博士毕业于中国科学院广州生物医药与健康研究院，之后赴斯坦福大学医学院进行博士后、讲师等工作。马宁研究员于2020年9月回国加入生物岛实验室，2022年1月加入广州实验室，课题组聚焦于心肺发育及慢性心肺疾病的发病机制研究。以第一作者发表论文于Circulation、Nature Biomedical Engineering和JBC等期刊，他引1300多次。曾获得广东省自然科学一等奖，广东省重大人才项目青年拔尖人才，黄埔区精英人才及美国AHA Postdoc Fellowship和AHA Career Development Award。

研究方向

1、心肺发育

2、慢性心肺疾病的发病机制

代表性第一和通讯作者论文：

（1）Belbachir N, Wu Y, Shen M, Zhang SL, Zhang JZ, Liu C, Knollmann BC, Lyon GJ^#, Ma N^#, Wu JC^#. Studying Long QT Syndrome Caused by NAA10 Genetic Variants Using Patient-Derived Induced Pluripotent Stem Cells. Circulation. 2023; 148:1598-1601.

（2）Barndt RJ*, Ma N*, Tang Y, Haugh MP, Alamri LS, Chan SY, Wu H. Modeling of dilated cardiomyopathy by establishment of isogenic human iPSC lines carrying phospholamban C25T (R9C) mutation (UPITTi002-A-1) using CRISPR/Cas9 editing. Stem Cell Research. 2021. doi:10.1016/j.scr.2021.102544.

（3）Ma N, Zhang S, Wu J. Complex heritability in cardiomyopathy. Nature Biomedical Engineering. 2019; 3:87-89.

（4）Ma N*, Zhang J*, Itzhaki I*, Zhang S, Chen H, Haddad S, Kitani T, Wilson K, Tian L, Shrestha S, Wu H, Lam C, Sayed N, Wu J. Determining the Pathogenicity of a Genomic Variant of Uncertain Significance Using CRISPR/Cas9 and Human Induced Pluripotent Stem Cells. Circulation. 2018; 138:2666–2681.

（5）Ma N*, Shan Y*, Liao B*, Kong G*, Wang C, Huang K, Zhang H., Cai X, Chen S, Pei D, Chen N, and Pan G. Factor-induced Reprogramming and Zinc Finger Nuclease-aided Gene Targeting Cause Different Genome Instability in beta-Thalassemia Induced Pluripotent Stem Cells (iPSCs). The Journal of Biological Chemistry. 2015; 290:12079-12089.

 （6）Ma N*, Liao B*, Zhang H, Wang L, Shan Y, Xue Y, Huang K, Chen S, Zhou X, Chen Y, Pei D, Pan G. Transcription activator-like effector nuclease (TALEN)-mediated gene correction in integration-free beta-thalassemia induced pluripotent stem cells. The Journal of Biological Chemistry. 2013; 288: 34671-34679.