【个人简介】

博士研究生，主任医师，教授，博士生导师，博士后合作导师，广州医科大学附属第三医院病理科主任，从事临床病理及科研近30年，致力于妇产科病理学临床和科学研究工作。先后于上海复旦大学妇产科医院和美国德克萨斯大学西南医疗中心进修妇科病理约两年,主译妇科圣经级图书《妇科病理学图谱》。

【研究方向】

妇科肿瘤发病机制

【科研项目】

1.2021年国家自然基金面上基金项目：雌激素甲基化途径调控下的PAX2失表达通过HSP90AA1/AKT/mTOR通路促进子宫内膜样癌发生发展的分子机制研究，项目批准号：82172935，54.7万 2022.1-2025.12

2.广州市科技局市校联合项目，202102010136，子宫内膜样癌中雌激素通过甲基化PAX2调控AKT泛素化促使AKT/mTOR通路活化，20万，2021.4.1-2023.3.31 结题，主持

3.广东省自然科学基金面上项目，2019A1515012194 鼻咽癌中EBV-miR-BART22通过靶向MAP2K4/ACADM-NTRK1调控YAP/HIF-1α介 导的糖酵解，10万，2019.10.1-2022-9-30，结题，主持

4.国家自然科学基金面上项目，81872198 蟾蜍毒素诱导miR-2110靶击FGFR1抑制鼻咽癌肿瘤干性、增殖和转移，60万，2019.01-2022.12，结题，第二主持。

5. 广州市科技计划项目,201904010037,Lnc-RNA-STYK1-2抑制膀胱癌进展的功能及机制研究, 20万，2019/4-2022/3,结题，第二主持。

【代表性论文及著作】

1. Chen H, Li L, Liu H, Qin P, Chen R, Liu S, Xiong H, Li Y, Yang Z, Xie M, Yang H, Jiang Q*. PAX2 is regulated by estrogen/progesterone through promoter methylation in endometrioid adenocarcinoma and has an important role in carcinogenesis via the AKT/mTOR signaling pathway. J Pathol. 2024 Jan 7. doi: 10.1002/path.6249. 

2.Wang, J., Zheng, N., Wan, H., Yao, Q., Jia, S., Zhang, X., Fu, S., Ruan, J., He, G., Chen, X., Li, S., Chen, R., Lai, B., Wang, J., Jiang, Q.*, Ouyang, N.*, & Zhang, Y*. (2024). Deep learning models for thyroid nodules diagnosis of fine-needle aspiration biopsy: a retrospective, prospective, multicentre study in China. The Lancet. Digital health, 6(7), e458–e469.

3.Yu, J. G., Wu, Z., Ming, Y., Deng, S., Wu, Q., Xiong, Z., Yu, T., Xia, G. S., Jiang, Q.*, & Li, Y*. (2023). Bayesian Collaborative Learning for Whole-Slide Image Classification. IEEE transactions on medical imaging, 42(6), 1809–1821.

4.Xiong Z, Zhang W, Liu S, Liu K, Wang J, Qin P, Liu Y, Jiang Q*. The combination of CD138/MUM1 dual-staining and artificial intelligence for plasma cell counting in the diagnosis of chronic endometritis. Am J Reprod Immunol. 2023 Mar;89(3):e13671.

5.Chen R, Zhang R, Zhang M, Liu S, Xie M, Yang Z, Shi Q, Chen H, Xiong H, Wang N, Jiang Q*. CIN grades possessing different HPV RNA location patterns and RNAscope is helpful tool for distinguishing squamous intraepithelial lesions in difficult cervical cases. Diagn Pathol. 2023 Feb 16;18(1):23.

6.Han Y, Shi MQ, Jiang QP, et al. Clinical Performance of the Xpert^® CT/NG Test for Detection of Chlamydia #trachomatis and Neisseria gonorrhoeae: A Multicenter Evaluation in Chinese Urban Hospitals. Front Cell Infect Microbiol. 2022;11:784610

7.Hui Chen#, Lingjun Li#, Ping Qin#, Hanzhen Xiong, Ruichao Chen, Minfen Zhang, Qingping Jiang*. A 4-gene signature predicts prognosis of uterine serous carcinoma. BMC Cancer. 2021;21(1):15

8.Zhang M, Chen H, Qin P, Cai T, Li L, Chen R, Liu S, Chen H, Lin W, Chen H, Strickland AL, Xiong H, Jiang Q. UPF1 impacts on mTOR signaling pathway and autophagy in endometrioid endometrial carcinoma. Aging (Albany NY). 2021 Sep 14;13(17):21202-21215.

9.Liu W, Cai T, Li L, Chen H, Chen R, Zhang M, Zhang W, Zhao L, Xiong H, Qin P, Gao X, Jiang Q. MiR-200a Regulats Nasopharyngeal Carcinoma Cell Migration and Invasion by Targeting MYH10. J Cancer. 2020 Mar 4;11(10):3052-3060. 

10.Liu Y^#， Jiang Q^#，Liu X，et al. Cinobufotalin powerfully reversed EBV-miR-BART22-induced cisplatin resistance via stimulating MAP2K4 to antagonize non-muscle myosin heavy chain IIA/glycogen synthase 3β/β-catenin signaling pathway. EBioMedicine.2019 Oct ;48 :386-404

11.Chen R, Zhang M, Liu W, Chen H, Cai T, Xiong H, Sheng X, Liu S, Peng J, Wang F, Chen H, Lin W, Xu X, Zheng W, Jiang Q*.Estrogen affects the negative feedback loop of PTENP1-miR200c to inhibit PTEN expression in the development of endometrioid endometrial carcinoma. Cell Death Dis.2019 Jan; 10(1): 4.

12.Wang Y, Chen H, Jiang Q et al. Effect of progestin usage on the interpretation of cervical high-grade squamous   intraepithelial lesion. Am J Surg Pathol.2019 08 ;43(8):1066-1073

13.江庆萍， 胡丹，王昀主译《妇科病理学图谱》第四版 ，中国科学技术出版社，2021

【所获荣誉和奖励】

 广州市高层次卫生人才：重点人才。2015-2019；2020-2024