汪学军,广州医科大学基础学院特聘教授,University of South Dakota(美国)基础生物医学部终身教授,研究方向:泛素蛋白酶体与心血管疾病。
教育经历(从大学本科开始,按时间倒排序):1998/8 – 2001/9, Cincinnati Children's Hospital Medical center, Cincinnati, Ohio (美国), 心血管分子生物学,博士后;1995/1-1998/8, University of South Dakota,Vermillion,South Dakota (美国), 解剖和结构生物学,博士 (PhD) ;1985/9-1988/6,湖北医科大学(现武汉大学医学部),病理生理学,硕士;1980/9-1985/6,湖北医科大学(现武汉大学医学部),临床医学,学士。
工作经历(科研与学术工作经历,按时间倒排序):2013/3-至今,广州医科大学,基础学院,特聘教授;2006/9-至今, University of South Dakota(美国),基础生物医学部,终身教授,博士生导师;2005/7-2006/8, University of South Dakota(美国),基础生物医学部,副教授;2001/10-2005/6, University of South Dakota(美国),基础生物医学部,助理教授 ;1998/8-2001/9,Cincinnati Children’s Hospital Medical Center(美国),分子心血管生物学, 博士后;1995/1-1998/7, University of South Dakota(美国),解剖和结构生物学系, 助研。1993/1-1994/12,湖北医科大学(现武汉大学医学部),病理生理学,副教授。
在研项目:1、国家自然科学基金面上项目,《胆红素调控心肌肥大发生发展的作用及机制》,编号81570278,2016/01-2019/12,经费57万,项目负责人。2、RO1 HL072166-11(11/1/2014 – 10/31/2018)NIH/NHLBI,US$1,450,000 (total cost) Ubiquitin receptors and cardiac proteotoxicity Role: 主持。3、R01 HL085629-09(3/1/2012 - 2/28/2016)NIH/NHLBIUS$1,430,000,(total cost) The COP9 Signalosome in the Heart,Role: 主持。4、11SDG6960011,Su (PI) (07/01/2011-06/30/2015)AHA Scientist Development Grant (National Center) $280,000 (total cost) The Ubiquitin Proteasome System in Diabetic Cardiomyopathy,Role: 参加。5、1 F32 HL122045,Terpstra (PI),Wang (Mentor),(07/01/2014 – 6/30/2017)NIH/NHLBI National Research Service Award,$162,000 (total cost),Direct proteasomal enhancement contributes to PKG-triggered cardioprotection,Role: 参加。
近年代表性论著(共48篇):
1.Tian Z§, Zheng H§, Li J, Li YF, Su H, and Wang X*. Genetically Induced Moderate Inhibition of the Proteasome in Cardiomyocytes Exacerbates Myocardial Ischemia-Reperfusion Injury in Mice. Circ Res 2012; 111(5): 532-542. (with companion editorial)
2. Huang H, Liu N, Guo H, Liao S, Li X, Yang C, Liu S, Song W, Liu C, Guan L, Li B, Xu L, Zhang C, Wang X, Dou QP, and Liu J. L-Carnitine Is an Endogenous HDAC Inhibitor Selectively Inhibiting Cancer Cell Growth In Vivo and In Vitro. PLoS One 2012; 7(11):e49062. doi: 10.1371/journal.pone.0049062.
3.Li X, Liu S, Huang H, Liu N, Zhao C, Liao S, Yang C, Liu Y, Zhao C, Li S, Lu X, Liu C, Guan L, Zhao K, Shi X, Song W, Zhou P, Dong X, Guo H, Wen G, Zhang C, Jiang L, Ma N, Li B, Wang S, Tan H, Wang X, Dou QP, and Liu J. Gambogic acid is a tissue-specific proteasome inhibitor in vitro and in vivo. Cell Reports 2013; 3(1): 211-22.
4.Rajagopalan V, Zhao M, Reddy S, Fajarado G, Wang X, Dewey S, Gomes AV, Bernstein D. Altered ubiquitin-proteasome signaling in right ventricular hypertrophy and failure. Am J Physiol Heart Circ Physiol 2013; 305(4):H551-62.