【个人简介】

邓冠华，硕士，副主任医师

2013.06-至今 广州市职业病防治院，从事职业健康防控工作。

【研究方向】

人体与环境微生物组；产业人群职业健康前置管理与持续风险防控；职业病危害智能监测预警与无人化装备应用；工程防护设计与应用；

【科研项目】

1.院企联合横向项目，“职业健康前控技术与管理研究 ”，2024-07-01至2025-12-31，15万，在研，主持。

2.院企联合横向项目，“东风日产乘用车公司职业健康前置管理研究”，2022-07-04至2025-12-31，10万，在研，主持。

3.市校（院）联合资助项目，“基于多组学筛选职业环境气溶胶微生物及其预防修复感染性肺损伤的机制研究”。2025-01-01至2026-12-31，20万，在研，主持。

4.市校（院）联合资助项目，地埋式净（污）水厂职业健康风险评估模型和风险控制技术及潜在资源开发利用关键技术研究。2025-01-01至2026-12-31，100万，在研，子项目主持。

【代表性论文及著作】

1. Yu T, Wu B, Zhang D, Deng G, Luo Y, Tang N, Shi Q, Hu F, Zhang G. Correction: A novel Bacillus aerolatus CX253 attenuates inflammation induced by Streptococcus pneumoniae in childhood and pregnant rats by regulating gut microbiome. Cell Mol Life Sci. 2024 Sep 10;81(1):390. doi: 10.1007/s00018-024-05405-x. Erratum for: Cell Mol Life Sci. 2024 Jul 29;81(1):319. doi: 10.1007/s00018-024-05232-0. PMID: 39254729; PMCID: PMC11387554.

2.Liu Y, Deng G, Liu H, Chen P, Pan Y, Chen L, Chen H, Zhang G. Seasonal variations of airborne microbial diversity in waste transfer stations and preventive effect on Streptococcus pneumoniae induced pulmonary inflammation. Sci Total Environ. 2024 Feb 20;912:168888. doi: 10.1016/j.scitotenv.2023.168888. Epub 2023 Nov 27. PMID: 38030004.

3.Luo Y, Zhang M, Huang S, Deng G, Chen H, Lu M, Zhang G, Chen L. Effects of tris (2-chloroethyl) phosphate exposure on gut microbiome using the simulator of the human intestinal microbial ecosystem (SHIME). Chemosphere. 2023 Nov;340:139969. doi: 10.1016/j.chemosphere.2023.139969. Epub 2023 Aug 25. PMID: 37634589.

4.Chen Y, Wu Y, Lv J, Zhou S, Lin S, Huang S, Zheng L, Deng G, Feng Y, Zhang G, Feng W. Overall and individual associations between per- and polyfluoroalkyl substances and liver function indices and the metabolic mechanism. Environ Int. 2024 Jan;183:108405. doi: 10.1016/j.envint.2023.108405. Epub 2023 Dec 22. PMID: 38163401.

5.Peng X, Yu KQ, Deng GH, Jiang YX, Wang Y, Zhang GX, Zhou HW. Comparison of direct boiling method with commercial kits for extracting fecal microbiome DNA by Illumina sequencing of 16S rRNA tags. J Microbiol Methods. 2013 Dec;95(3):455-62. doi: 10.1016/j.mimet.2013.07.015. Epub 2013 Jul 27. PMID: 23899773.

6.Liu MB, Xu SR, He Y, Deng GH, Sheng HF, Huang XM, Ouyang CY, Zhou HW. Diverse vaginal microbiomes in reproductive-age women with vulvovaginal candidiasis. PLoS One. 2013 Nov 12;8(11):e79812. doi: 10.1371/journal.pone.0079812. PMID: 24265786; PMCID: PMC3827160.

7.He Y, Zhou BJ, Deng GH, Jiang XT, Zhang H, Zhou HW. Comparison of microbial diversity determined with the same variable tag sequence extracted from two different PCR amplicons. BMC Microbiol. 2013 Sep 14;13:208. doi: 10.1186/1471-2180-13-208. PMID: 24034943; PMCID: PMC3848352.

8.Jiang XT, Peng X, Deng GH, Sheng HF, Wang Y, Zhou HW, Tam NF. Illumina sequencing of 16S rRNA tag revealed spatial variations of bacterial communities in a mangrove wetland. Microb Ecol. 2013 Jul;66(1):96-104. doi: 10.1007/s00248-013-0238-8. Epub 2013 May 7. PMID: 23649297.

9.实用新型专利：一种工作场所环境空气采样装置，专利号:ZL202121426409.1，授权公告日:2022年01月11日。

【所获荣誉和奖励】

1.获“百佳优秀学术论文奖”、省级“优秀论文奖”等;