【个人简介】
丘福满,医学博士,副教授,博士生导师。现任广东省流行病学会青年委员会常务委员,广东省热带医学学会理事;广州市高层次人才青年后备人才,广东省新病毒疫苗预防接种异常反应调查诊断专家组专家,国家自然科学基金及广东省自然科学基金项目通讯评审专家。担任BMC Cancer、BMC Medical Genetics、Cancer Cell International等杂志的Editorial Board Member、reviewers。长期从事肿瘤分子流行病学、生物标志物及生物统计学方法应用等领域的研究工作,在复杂疾病的易感机制及表观修饰等方面具有较好的工作基础。近年来,负责主持国家自然科学基金项目2项和省市级课题3项。其研究成果包括在Clin Cancer Res, Plos genet等国际著名刊物发表研究论文50余篇,其中作为通讯作者或第一作者(含并列)的SCI论文>15篇。参编论著《肿瘤分子流行病学》和本科教材《预防医学:案例版》各1部。获得国家授权发明专利2项;获教育部高等学校优秀成果奖自然科学奖二等奖1项。
【研究方向】
分子流行病学
【科研项目】
1.国家自然科学基金面上项目, 长链非编码RNA Linc02076影响卵巢癌转移和预后的机制研究,2019-01-01至2022-12-31,57万,结题,主持。
2.国家自然科学基金青年科学基金项目,反义长链非编码RNA HHIP-AS1调控hedgehog信号通路影响子宫内膜癌发生发展的机制研究,2017-01-01至2019-12-31,17万,结题,主持。
3.广州市科技计划项目,基于RNA-Seq筛选的功能性LincRNA在子宫内膜癌发生发展的作用及分子机制研究,2017-05-01至2020-04-30,20万,结题,主持。
【代表性论文及著作】
1.Qiu F, Yang L, Ling X, Yang R, Yang X, Zhang L, Fang W, Xie C, Huang D, Zhou Y, Lu J. Sequence Variation in Mature MicroRNA-499 Confers Unfavorable Prognosis of Lung Cancer Patients Treated with Platinum-Based Chemotherapy. Clin Cancer Res. 2015 Apr 1;21(7):1602-13.
2.Qiu F, Yang L, Lu X, Chen J, Wu D, Wei Y, Nong Q, Zhang L, Fang W, Chen X, Ling X, Yang B, Zhang X, Zhou Y, Lu J. The MKK7 p.Glu116Lys Rare Variant Serves as a Predictor for Lung Cancer Risk and Prognosis in Chinese. PLoS Genet. 2016 Mar 30;12(3): e1005955.
3.Qiu F, Li Y, Lu X, Xie C, Nong Q, Wu D, Chen J, Yang L, Zhou Y, Lu J. Rare variant of MAP2K7 is associated with increased risk of COPD in southern and eastern Chinese. Respirology. 2017 May;22(4):691-698.
4.Wei Gong# Yinyan Li#, Jianfeng Xian, Lei Yang, Yuanyuan Wang, Xin Zhang, Yifeng Zhou, Xinhua Wang, Guibin Qiao, Cuiyi Chen, Soham Datta, Xincheng Gao, Jiachun Lu*, Fuman Qiu*. Long non-coding RNA LSAMP-1 is down-regulated in non-small cell lung cancer and predicts a poor prognosis. Cancer Cell Int, 2022 May 6;22(1):181.
5.Yonghui Yu#, Yiwen Zhang#, Zhi Li, Yongshun Dong, Hongmei Huang, Eryong Zhao, Yongxiu Chen, Lei Yang, Jiachun Lu, Binyao Yang, Fuman Qiu*. An EMT-related genes signature as a prognostic biomarker for patients with endometrial cancer. BMC cancer, 2023 Sep 18;23(1):879.
6.Hongmei Huang, Jiaji Gu, Xinjie Kuang, Yonghui Yu, Boqi Rao, Shenying Fang, Jiachun Lu, Fuman Qiu*. An integrative pan-cancer analysis of WWC family genes and functional validation in lung cancer. Cell Signal. 2024 Mar:115:111034.
7.Yongshun Dong#, Zili Zhang#, Hongmei Huang#, Yonghui Yu, Boqi Rao, Xinjie Kuang, Jie Zeng, Eryong Zhao, Yongxiu Chen, Jiachun Lu, Fuman Qiu*. ZFHX2-AS1 interacts with DKC1 to regulate ARHGAP5 pseudouridylation and suppress ovarian cancer progression. Cell Signal. 2024 Oct 3:124:111441.
8.Yingyi Feng#, Yongshun Dong#, Boqi Rao#, Yonghui Yu, Wenpeng Su, Jie Zeng, Eryong Zhao, Yongxiu Chen, Shenying Fang, Yifeng Zhou, Jiachun Lu, Fuman Qiu*. A novel LINC00478 serves as a tumor suppressor in endometrial carcinoma progression. J Cancer Res Clin Oncol. 2023 Nov;149(16):14927-14940.
【所获荣誉和奖励】
1.2017年荣获教育部高等学校优秀成果奖自然科学奖二等奖(第8完成人)