李艳丽，女，理学博士，南山学者特聘副教授。2021年毕业于华东师范大学，师从步文博教授；随后进入广州医科大学药学院工作。目前已在Angew. Chem. Int. Ed., ACS nano, Nano today等期刊共发表论文12篇。近五年来，以第一、共一或通讯作者身份发表论文8篇，6篇IF>10。。

联系邮箱：ylli@gzhmu.edu.cn

研究方向

1、无机及有机/无机杂化纳米材料的设计、合成及功能化

2、功能纳米材料介导的肿瘤治疗及免疫、抗菌研究

主要科研项目

1、国家自然科学基金青年项目，2023/01-2025/12，在研，主持

2、广州市科技局基础与应用基础研究项目，2023/04-2025/03，在研，主持

3、广州医科大学高水平大学人才引进项目，2022/01-2027/01，在研，主持

主要论文及著作（代表性）

1、Yanli Li, Teng Gong*, Hongbao Gao, Yang Chen, Huiyan Li, Peiran Zhao, Yaqin Jiang, Kun Wang, Yelin Wu, Xiangpeng Zheng*, and Wenbo Bu*. ZIF-Based Nanoparticles Combine X-Ray-Induced Nitrosative Stress with Autophagy Management for Hypoxic Prostate Cancer Therapy, Angew. Chem. Int. Ed., 2021, 60, 15472-15481. (IF=16.826)

2、Yanli Li, Peiran Zhao, Teng Gong*, Han Wang, Xingwu Jiang, Hui Cheng, Yanyan Liu, Yelin Wu*, and Wenbo Bu*. Redox Dyshomeostasis Strategy for Hypoxic Tumor Therapy Based on DNAzyme-Loaded Electrophilic ZIFs, Angew. Chem. Int. Ed., 2020, 59, 22537-22543. (IF=16.826)

3、Fan Wu†, Yanli Li† (co-first authors), Yun Meng†, Xuechao Cai, Jieyun Shi, Jinjin Li, Yang Chen, Li Zhang, Xianfu Meng, Huiyan Li, Xingwu Jiang, Zhenxiao Fu, Yelin Wu*, Wenbo Bu*. An Ion-Enhanced Oncolytic Virus-Like Nanoparticle for Tumor Immunotherapy, Angew. Chem. Int. Ed., 2022, 61, e202210487. (IF=16.826)

4、Jianwen Huang, Shuai Wang, You Zhou, Qiuxia Li, Jing Yin b, Dailong Zha, Junyang Zhong, Wenmin Zhou, Chengkun Zheng, Yingling Miao, Wenjie Chen, Chuanshan Xu*, Yanli Li*, Teng Gong*. Nanoformulations mediated metastasis brake in cancer therapy via photodynamic-enhanced ferroptosis and regional inflammation management, Chem. Eng. J., 2023, 451, 138585. (IF=16.744)

5、Teng Gong†, Yanli Li† (co-first authors), Bin Lv†, Han Wang, Weiqiang Ge, Yanyan Liu*, Wei Yang, Yelin Wu, Xingwu Jiang, Hongbo Gao, Xiangpeng Zheng*, and Wenbo Bu*. Full-Process Radiosensitization Based on Nanoscale Metal-Organic Frameworks, ACS Nano, 2020, 14, 3032-3040. (IF=18.027)

6、Yelin Wu†, Yanli Li† (co-first authors), Guanglei Lv*, and Wenbo Bu*. Redox Dyshomeostasis Strategy for Tumor Therapy Based on Nanomaterials Chemistry, Chem. Sci., 2022, 13, 2202-2217. (IF=9.969)

7、Yanli Li† (co-first authors), Xiaonan Gao†, Zhengze Yu, Bo Liu, Wei Pan, Na Li*, and Bo Tang*. Reversing Multidrug Resistance by Multiplexed Gene Silencing for Enhanced Breast Cancer Chemotherapy, ACS Appl. Mater. Interfaces, 2018, 10, 15461-15466. (IF=10.383)

8、Na Li†, Yanli Li† (co-first authors), Xiaonan Gao, Zhengze Yu, Wei Pan, and Bo Tang*. Multiplexed gene silencing in living cells and in vivo using a DNAzymes-CoOOH nanocomposite, Chem. Commun., 2017, 53, 4962-4965. (IF=6.065)