【个人简介】
男,广东南海人,医学博士,教授,博士生导师,享受国务院"政府特殊津贴"。1984年毕业于广州中医药大学中医学专业,1990年获医学博士学位,美国国立卫生研究院(NIH)高级访问学者。历任广州中医药大学热带医学研究所副所长、党总支书记、外事处处长(国际学院院长)、副校长,广州医科大学党委常委、党委副书记、校长,广州医科大学中西医结合学科带头人。
【研究方向】
中西医结合呼吸疾病
【科研项目】
1.国家自然科学基金面上项目,《基于伏邪理论的冠状病毒感染病证结合模型构建及分消伏湿法干预研究》,2021.01至2024.12,55万,在研,主持。
2.国家中医药管理局项目,《中西医结合临床高水平学科建设项目》,2023-2026,200万,在研,主持。
3.国家自然科学基金委国家自然科学基金-云南联合,《滇药臭灵丹靶向流感病毒和宿主免疫调节的新型活性成分药效机制及构效关系研究》,2016.01 至 2019.12,40万,结题,主持。
【代表性论文及著作】
题目 | 发表时间 | 刊物名称 | 影响因子 |
Utilizing network pharmacology and experimental validation to investigate the underlying mechanism of Denglao Qingguan decoction against HCoV-229E | 2024.05 | Heliyon | IF:3.400 |
Generation of a pdmH1N1 2018 Influenza A Reporter Virus Carrying a mCherry Fluorescent Protein in the PA Segment | 2022.01 | Front Cell Infect Microbio | IF:5.900 |
Lianhuaqingwen capsule inhibits non-lethal doses of influenza virus-induced secondary Staphylococcus aureus infection in mice | 2022.10 | J Ethnopharmacol
| IF:5.300 |
Liu Shen Wan inhibits influenza virus-induced secondary Staphylococcus aureus infection in vivo and in vitro | 2021.09 | J Ethnopharmacol
| IF:5.300 |
Antigenic Drift of the Hemagglutinin from an Influenza A (H1N1) pdm09 Clinical Isolate Increases its Pathogenicity In Vitro | 2021.10 | Virol Sin | IF:4.900 |
Lianhuaqingwen capsule inhibits influenza-induced bacterial adhesion to respiratory epithelial cells through down-regulation of cell adhesion molecules. | 2021.10 | J Ethnopharmacol
| IF:5.300 |
Chaiqin Qingning Capsule Inhibits Influenza Virus Infection and Inflammation In Vitro and In Vivo. Evid Based Complement Alternat Med. | 2021.09 | Evid Based Complement Alternat Med | IF:3.014 |
Characterization and Evolutionary Analysis of a Novel H3N2 Influenza A Virus Glycosylation Motif in Southern China | 2020.06 | Front Microbiol | IF:5.900 |
Effect of eleutheroside B1 on non‑coding RNAs and protein profiles of influenza A virus‑infected A549 cells | 2020.03 | Int J Mol Med | IF:4.800 |
Efficacy and safety of Chou-Ling-Dan granules in the treatment of seasonal influenza via combining Western and traditional Chinese medicine: protocol for a multicentre, randomised controlled clinical trial | 2019.04 | BMJ Open | IF:2.900 |
Pterodontic acid isolated from Laggera pterodonta suppressed IG-I/NF-KB/STAT1/Type I interferon and programmed death-ligand 1/2 activation induced by influenza A virus in vitro | 2019.12 | Inflammopharmacology | IF:5.400 |
Effects of indole alkaloids from leaf of Alstonia scholaris on post-infectious cough in mice | 2018.03 | Journal of Ethnopharmacology | IF:5.300 |
Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation | 2018.09 | International Journal of Molecular Medicine | IF:4.800 |
【所获荣誉和奖励】
1.2019年获广东省教育教学成果奖一等奖,排名第一
2.2020年获云南省卫生科技成果奖励一等奖,排名第二