【个人简介】
赖毛华,医学博士,主任医师,硕士生导师,博士生导师。长期从事中西医结合生殖内分泌疾病基础与临床研究,在多囊卵巢综合征和复发性流产方面有极深的造诣。擅长将传统中医药学与现代人类辅助生殖技术结合解决临床复杂生殖疑难问题。现任国际传统与现代生殖医学协会常务理事,世界中医药联合会妇科分会理事,广东省第七、八届中西医结合学会理事,广东省中西医结合生殖委员会主任委员,中国中西医结合生殖委员会委员,国家自然基金同行评议专家,广东省自然基金评议专家,湖南省自然基金评议专家,湖北省自然基金评议专家,江苏省科技咨询专家库专家,广西科技奖励专家库专家等职务。
【研究方向】
中西医结合临床;中西医结合生殖内分泌疾病研究
【科研项目】
1.国家自然科学基金面上项目, 从线粒体适应性研究中药调节PCOS胎盘功能以改善子代健康的机制,2024-1-01至2027-12-31,45万,在研,参与。
2.国家自然科学基金面上项目,基于水通道蛋白探讨电针改善超促排卵PCOS大鼠卵母细胞质量和发育潜能的作用与机制,2018-1-01至2021-12-31,57万,结题,主持
3.国家自然科学基金面上项目,基于miR-21调控PTEN/PI3K信号途径探讨针刺改善PCOS卵巢局部IR的机制,2018-1-01至2021-12-31,57万,结题,参与
4.国家自然科学基金青年基金项目,从PI3K/Akt通路探讨针刺调控PCOS子宫内膜局部IR促进胚胎着床的机制,2014-1-01至2016-12-31,23万,结题,主持
【代表性论文及著作】
1. Effect of acupuncture and metformin on insulin sensitivity in women with polycystic ovary syndrome and insulin resistance: a three-armed randomized controlled trial. Hum Reprod. 2022,37(3):542-552.
2. Polycystic ovary syndrome is an independent risk factor for hypertensive disorders of pregnancy: A systematic review, meta-analysis, and meta-regression. Endocrine. 2021 Dec;74(3):518-529.
3.Chemerin isoform analysis in human biofluids using an LC/MRM-MS-based targeted proteomics approach with stable isotope-labeled standard. Anal Chim Acta. 2020,1139:79-87.
4.A prospective pilot study of the effect of acupuncture on insulin sensitivity in women with polycystic ovary syndrome and insulin resistance. Acupunct Med. 2020 Oct;38(5):310-318.
5. A multicenter randomized trial of personalized acupuncture, fixed acupuncture, letrozole, and placebo letrozole on live birth in infertile women with polycystic ovary syndrome. Trials. 2020,21(1):239.
6. Circular RNA expression profiling of granulosa cells in women of reproductive age with polycystic ovary syndrome. Arch Gynecol Obstet. 2019 Aug;300(2):431-440.
7.acupuncture treatment for insulin sensitivity of women with polycystic ovary syndrome and insulin resistance: a study protocol for a randomized controlled trial. Trials. 2017 Mar 9;18(1):115.
8.Cryptotanshinone Regulates Androgen Synthesis through the ERK/c-Fos/CYP17 Pathway in Porcine Granulosa Cells. Evid Based Complement Alternat Med. 2017;2017:5985703.
9.Comparison of acupuncture pretreatment followed by letrozole versus letrozole alone on live birth in anovulatory infertile women with polycystic ovary syndrome: a study protocol for a randomised controlled trial. BMJ Open. 2016 Oct 7;6(10):e010955.
10. Effectiveness of abdominal acupuncture for patients with obesity-type polycystic ovary syndrome: a randomized controlled trial. J Altern Complement Med. 2013 Sep;19(9):740-5.
11.腹针对肥胖型多囊卵巢综合征患者内分泌及糖脂代谢的影响[J].针刺研究,2010,35(04):298-30
12.中医妇科特色疗法。中国中医药出版社,2022.6出版, 副主编
【所获荣誉和奖励】
1.2014年广东省科技进步二等奖;
2.2015年广州市医学骨干人才
2.2018年广东省首批杰出青年医学人才
3.2020年广州市第三批优秀中医临床人才