个人简介
陈贲，医学博士，副教授、副研究员、主治医师，广州医科大学南山学者，广州医科大学附属脑科医院认知中心主任，曾留学于德国德累斯顿工业大学。长期围绕认知与情绪障碍、嗅觉神经科学及阿尔茨海默病早期诊疗开展临床、基础与转化研究，结合多模态磁共振、多组学、电生理、神经调控等技术探索疾病早期识别、机制分层与精准干预。以第一/通讯作者发表论文50余篇。主持国家自然科学基金面上项目与青年科学基金，广东省自然科学基金2项、广州市卫生健康委员会重点项目等共10项。获授权发明专利2项、实用新型专利4项，申请2项发明专利。获广东省科技进步奖二等奖、中国仪器仪表学会科学技术进步二等奖、2025年度创新广州科技进步奖一等奖等；获中国医师协会精神科医师分会“青年精神科医师希望之星”、广州市卫生健康委员会优秀人才等荣誉。
主要研究方向
· 阿尔茨海默病谱系的嗅觉、血液标志物与多模态影像早期识别。
· 老年抑郁症认知障碍及嗅觉相关脑网络与神经环路机制。
· 嗅觉训练与嗅区神经调控对认知与情绪障碍的干预效果与起效机制。
主持科研项目
1. 国家自然科学基金面上项目（82672020），“嗅觉训练通过恢复梨状皮质兴奋/抑制平衡改善抑郁症认知障碍的神经环路机制研究”，2027.01–2030.12，经费49万元。
2. 国家自然科学基金青年科学基金项目（82101508），“内嗅皮层功能增强在减轻主观认知下降人群的气味识别受损中的 fMRI 研究”，2022.01–2024.12，经费30万元。
3. 广东省自然科学基金面上项目（2026A151501212），“嗅觉训练通过 cAMP-PKA 信号通路恢复梨状皮质 E/I 平衡改善老年抑郁症认知障碍的机制研究”，2026.01–2028.12，经费10万元。
4. 广东省自然科学基金面上项目（2024A1515011035），“海马-内侧隔核胆碱能环路介导嗅觉训练改善阿尔茨海默病记忆受损的机制研究”，2024.01–2026.12，经费15万元。
5. 广州市卫生健康委员会基础研究计划/市校（院）企联合资助重点项目（2023A03J0840），“伴嗅觉识别受损的老年抑郁症患者的内嗅-海马环路功能紊乱与痴呆风险研究”，2023.04–2025.03，经费50万元。
6. 南方神经精神医学青年医生临床合作专项（2025GDMHA00），“嗅觉环路影像组学联合血浆 p-tau217 的阿尔茨海默疾病早期诊断：多队列验证与中介机制研究”，2026.04–2026.12，经费4万元。
7. 广州市基础研究计划基础与应用基础研究项目（202201010491），“主观认知下降人群的嗅觉信息上行与下行加工异常的 fMRI 研究”，2022.04–2024.03，经费5万元。
8. 广州市中医药和中西医结合科技项目（20222A011013），“主观认知下降人群的内嗅皮层功能增强代偿气味阈值介导的气味识别受损的 fMRI 研究”，2022.05–2024.04，经费1.5万元。
第一/通讯作者发表论文（50篇）
1. Ben Chen, Haishan Shi, Le Hou , Xiaomei Zhong, Yanhua Wang, Zhangying Wu, Qi Peng, Dong Zheng, Yuefen Zhang, Yan Tan, Ziyan Fang, Xinru Chen , Xinni Luo, Sha Liu, Yuping Ning*. Medial temporal lobe atrophy as a predictor of poor cognitive outcomes in general paresis. Early Intervention in Psychiatry. 2017;13:30-38.
2. Ben Chen, Xiaomei Zhong, Naikeng Mai, Qi Peng, Zhangying Wu, Cong Ouyang, Weiru Zhang , Wanyuan Liang, Yujie Wu, Sha Liu, Lijian Chen, Yuping Ning*. Cognitive Impairment and Structural Abnormalities in Late Life Depression with Olfactory Identification Impairment: an Alzheimer’s Disease-Like Pattern. International Journal of Neuropsychopharmacology. 2018;21(7):640-648.
3. Ben Chen, Xiaomei Zhong, Naikeng Mai, Qi Peng, Min Zhang, Xinru Chen, Zhangying Wu, Laiquan Zou, Wanyuan Liang, Cong Ouyang, Yujie Wu, Yuping Ning*. Interactive Effect of Depression and Cognitive Impairment on Olfactory Identification in Elderly People. Journal of Alzheimer’s Disease. 2018;66(4):1645-1655.
4. Ben Chen*, Joshi Akshita, Pengfei Han, Divesh Thaploo, Hagen H. Kitzler, Thomas Hummel. Aberrancies of Brain Network Structures in patients with Anosmia. Brain Topography. 2020;33(3),403-411.
5. Ben Chen*, Rita Klarmann, Matthias Israel, Yuping Ning, Romain Colle, Thomas Hummel. Difference of olfactory deficit in patients with acute episode of schizophrenia and major depressive episode. Schizophrenia Research. 2019;212:99-106.
6. Ben Chen*, Antje Haehner, Mehmet Kibris Mahmut, Thomas Hummel. Faster olfactory adaptation in patients with olfactory deficits: an analysis of results from odor threshold testing. Rhinology. 2020;58(5):489-494.
7. Ben Chen#, Qiang Wang#, Xiaomei Zhong#, Lena Heyne, Yuping Ning*, Thomas Hummel. Can we assess the sense of smell through a face mask? International Forum of Allergy & Rhinology. 2020;10(11):1264-1265.
8. Ben Chen*, Alexander Pfister, Philipp Nahrath, Thomas Hummel. Odor perception depends on airflow, odor solubility and intranasal application site. Rhinology. 2020;58(6):635-637.
9. Simona Negoias#, Ben Chen#*, Emilia Iannilli, Yuping Ning, Hagen H Kitzler, Thomas Hummel, Stephanie Krueger. Odor-related brain hyper-reactivity in euthymic bipolar disorder: An fMRI and ERP study. Psychiatry Research. 2019;278:218-227.
10. Qiang Wang#, Ben Chen#, Xiaomei Zhong#, Huarong Zhou, Min Zhang, Naikeng Mai, Zhangying Wu, Xingxiao Huang, Antje Haehner, Xinru Chen, Lavinia Alberi Auber, Qi Peng, Thomas Hummel, Yuping Ning*. Olfactory dysfunction is already present in subjective cognitive decline and deepens with disease severity in the Alzheimer’s disease spectrum. Journal of Alzheimer’s Disease. 2021;79(2):585-595.
11. Ben Chen#, Xiaomei Zhong#, Min Zhang, Naikeng Mai, Zhangying Wu, Xinru Chen, Qi Peng, Huarong Zhou, Qiang Wang, Mingfeng Yang, Si Zhang, Lavinia Alberi Auber, Ilona Croy, Thomas Hummel, Yuping Ning*. The additive effect of late-life depression and olfactory dysfunction on the risk of dementia was mediated by hypersynchronization of the hippocampus/fusiform gyrus. Translational Psychiatry. 2021,;11(1):172.
12. Yunpeng Zang #*, Ben Chen#, Thomas Hummel. Assessment of odor perception related to stimulation modes in a mock MRI scanner. Journal of neuroscience methods. 2020;341.108754.
13. Ben Chen*, Cara Benzien, Vanda Faria, Yuping Ning, Mandy Cuevas, Jana Linke, Ilona Croy, Antje Haehner, Thomas Hummel. Symptoms of depression in patients with chemosensory disorders. ORL-Journal for Oto-Rhino-Laryngology Head and Neck Surgery, 2021;83(3):135-143.
14. Ben Chen* , Carla Masala, Anna Oleszkiewicz , Verena Englmeier, Nadine Gunder, Susanne Menzel, Antje Hähner , Thomas Hummel. Nonlinear association between chemosensory dysfunction and body mass index. Journal of Sensory Studies.
15. Ben Chen*, Melanie Espin, Robert Haussmann, Claudia Matthes, Markus Donix, Thomas Hummel, Antje Haehner. The effect of olfactory training on olfaction, cognition, and brain function in patients with mild cognitive impairment. Journal of Alzheimer's Disease. 2021. 85(2):745-754.
16. Min Zhang, Ben Chen, Xiaomei Zhong, Huarong Zhou, Qiang Wang, Naikeng Mai, Zhangying Wu, Xinru Chen, Qi Peng, Si Zhang, Minfeng Yang, Gaohong Lin, Yuping Ning. Neuropsychiatric symptoms exacerbate the cognitive impairments in patients with late-life depression. Frontiers in Psychiatry. 2021, 12:757003.
17. Ben Chen#, Qiang Wang ,Xiaomei Zhong, Naikeng Mai, Min Zhang, Huarong Zhou, Antje Haehner, Xinru Chen , Zhangying Wu, Lavinia Alberi Auber, Dongping Raoa, Wentao Liu, , Jinhong Zheng, Lijing Lin, Nanxi Li, Sihao Chen, Bingxin Chen, Thomas Hummel, Yuping Ning. Structural and functional abnormalities of olfactory-related regions in subjective cognitive decline, mild cognitive impairment and Alzheimer's disease. International Journal Of Neuropsychopharmacology. 2021; 25(5):361-374.
18. Qiang Wang, Ben Chen#, Xiaomei Zhong, Huarong Zhou, Min Zhang, Naikeng Mai, Zhangying Wu, Xinru Chen, Mingfeng Yang, Si Zhang, Gaohong Lin, Thomas Hummel, Yuping Ning. Neuropsychiatric symptoms mediated the relationship between odour identification and cognition in Alzheimer's disease spectrum: a structural equation model analysis. Frontiers In Aging Neuroscience 2022. 12;13:732840.
19. Meiling Liu#, Ben Chen#, Xiaomei Zhong#, Min Zhang, Qiang Wang, Huarong Zhou, Zhangying Wu, Le Hou, Qi Peng, Si Zhang, Minfeng Yang, Gaohong Linand Yuping N*. Differences in Odor Identification in Early-Onset and Late-Onset Depression. Brain Science. 2022. 16;12(2):276.
20. Mingfeng Yang#, Ben Chen#, Xiaomei Zhong#, Huarong Zhou, Naikeng Mai, Min Zhang, Zhangying Wu, Qi Penga, Qiang Wang, Meiling Liu, Si Zhang, Gaohong Lin, Thomas Hummelc, Yuping Ning*. Disrupted olfactory functional connectivity in patients with late-life depression. Journal of Affective Disorders. 2022. 12;S0165-0327(22)00253-1
21. Si Zhang#, Ben Chen#, Xiaomei Zhong#, Min Zhang, Qiang Wang, Zhangying Wu, Le Hou, Huarong Zhou, Xinru Chen, Meiling Liu, Mingfeng Yang, Gaohong lin, Thomas Hummel, Yuping Ning*. Interactive Effect of Agitation and Cognitive Impairment on Odor Identification in Patients with Late-Life Depression. Frontiers in Psychiatry, 2022. 13:839012
22. Gaohong Lin#, Zhangying Wu#, Ben Chen#, Min Zhang, Qiang Wang, Meiling Liu, Si Zhang, Mingfeng Yang, Yuping Ning *, Xiaomei Zhong *. Altered Microstate Dynamics and Spatial Complexity in Late-Life Schizophrenia. Frontiers in Psychiatry. 2022;13:907802.
23. Haehner A#*, Chen B#*, Espin M, Haussmann R, Matthes C, Desser D, Loessner L, Brandt MD, Donix M, Hummel T. Training with Odors Impacts Hippocampal Thickness in Patients with Mild Cognitive Impairment. Journal Of Alzheimers Disease. 2022;88(2):743-755.
24. Xiaomei Zhong#, Ben Chen#, Le Hou#, Qiang Wanga, Meiling Liu, Mingfeng Yang, Min Zhang, Huarong Zhou, Zhangying Wu, Si Zhang, Gaohong Lin, Yuping Ning*. Shared and specific dynamics of brain activity and connectivity in amnestic and nonamnestic mild cognitive impairment. CNS Neuroscience & Therapeutics, 2022, 28(12):2053-2065.
25. Qiang Wang#, Ben Chen#, Xiaomei Zhong#, Le Hou, Min Zhang, Mingfeng Yang, Zhangying Wu, Xinru Chen, Naikeng Mai, Huarong Zhou, Gaohong lin, Si Zhang, Yuping Ning*. Static and dynamic functional connectivity variability of the anterior-posterior hippocampus with subjective cognitive decline. Alzheimer's Research & Therapy, 2022, 3;14(1):122.
26. Ben Chen#, Mingfeng Yang#, Xiaomei Zhong#, Qiang Wang, Huarong Zhou, Meiling Liu, Min Zhang, Le Hou, Zhangying Wu, Si Zhang, Gaohong Lin, Yuping Ning*. Disrupted dynamic functional connectivity of hippocampal subregions mediated the slowed information processing speed in late-life depression. Psychological Medicine, 2023, 53(14):1-11.
27. Ben Chen*, Anabel Stein, Falk-Tony Olesch, Thomas Hummel. Odor deprivation influences human olfactory function. Physiol Behav. 2023,19;262:114090.
28. Mingfeng Yang#, Ben Chen#, Huarong Zhou, Naikeng Mai, Min Zhang, Zhangying Wu, Qi Peng, Qiang Wang, Meiling Liu, Si Zhang, Gaohong Lin, Jingyi Lao, Yijie Zeng, Xiaomei Zhong*, Yuping Ning*. Relationships Among Short Self-Reported Sleep Duration, Cognitive Impairment, and Insular Functional Connectivity in Late-Life Depression. Journal of Alzheimers Disease. 2023
29. Gaohong Lin#, Ben Chen#, Mingfeng Yang#, Zhangying Wu, Kaijie Qiu, Min Zhang, Qiang Wang, Si Zhang, Jingyi Lao, Yijie Zeng, Yuping Ning* and Xiaomei Zhong*. Lower Dorsal Lateral Prefrontal Cortex Functional Connectivity in Late-Life Depression with Suicidal Ideation. The American journal of geriatric psychiatry. 2023
30. Ben Chen*, Anika Bossen, Falk-Tony Olesch, Thomas Hummel. A Life Without Smell: Olfactory Function in People Working in Odorless Rooms. Laryngoscope. 2023.
31. Ting Su#, Ben Chen#, Mingfeng Yang, Qiang Wang, Huarong Zhou, Min Zhang, Zhangying Wu, Gaohong Lin, Danpeng Wang, Yue Li, Xiaomei Zhong, Yuping Ning. Disrupted functional connectivity of the habenula links psychomotor retardation and deficit of verbal fluency and working memory in late-life depression. CNS Neuroscience & Therapeutics
32. Ben Chen#, Mingfeng Yang#, Meiling Liu, Qiang Wang, Huarong Zhou, Min Zhang, Le Hou, Zhangying Wu, Si Zhang, Gaohong Lin, Xiaomei Zhong, Yuping Ning, Differences in olfactory functional connectivity in early-onset depression and late-onset depression, Psychoradiology, 2023,3, kkad030
33. Ben Chen#, Ting Su#, Mingfeng Yang, Qiang Wang, Huarong Zhou, Guili Tan, Siting Liu, Zhangying Wu, Xiaomei Zhong , Yuping Ning. Static and dynamic functional connectivity of the habenula in late-life depression patient with suicidal ideation. Journal of Affective Disorders. 2024 356:499-506.
34. Shuang Liang#, Ben Chen#, Meiling Liu, Qiang Wang, Mingfeng Yang, Gaohong Lin, Danyan Xu, Yijie Zeng, Jingyi Lao, Jiafu Li, Qin Liu, Kexin Yao, Zhangying Wu, Min Zhang, Wenyue Shi , Linglong Qin , Xiaomei Zhong, Yuping Ning. Olfactory Dysfunction as a Marker for Cognitive Impairment in General Paresis of the Insane: A Clinical Study. Med Sci Monit. 2024 Jul 25;30:e944243
35. Jiafu Li#, Ben Chen#, Qiang Wang, Danyan Xu, Hanna Lu, Gaohong Lin, Mingfeng Yang, Jingyi Lao, Yijie Zeng, Shuang Liang, Kexin Yao, Qin Liu, Yuanling Huang, Xiaoxi Liu, Xiaomei Zhong, Yuping Ning. Chemosensory anhedonia facilitates depressive symptoms and cognitive impairment in late-life depression. Geriatrics & Gerontology International. . 2024;24(10):1022-1029
36. Danyan Xu#, Ben Chen#, Mingfeng Yang, Gaohong Lin, Min Zhang, Zhangying Wu, Huarong Zhou, Xiaolei Shi, Qi Peng, Yijie Zeng, Jingyi Lao, Qiang Wang, Shuang Liang, Jiafu Li, Kexin Yao, Qin Liu, Yanhong Ou, Xiaomei Zhong*, Yuping Ning. Odor identification dysfunction in late-life depression with suicidal ideation. J Affect Disord. 2024 :367:768-776.
37. Qin Liu#, Ben Chen#, Qiang Wang, Danyan Xu, Mingfeng Yang, Gaohong Lin, Yijie Zeng, Jingyi Lao, Shuang Liang, Jiafu Li, Kexin Yao, Xiaomei Zhong2*, Yuping Ning. Sex differences in the relationship between olfactory and cognitive impairment among subjects with subjective cognitive decline and mild cognitive impairment. Biol Sex Differ. 2025 13;16(1):12.
38. Ting Su#, Ben Chen#, Qin Liu, Yunheng Chen, Mingfeng Yang, Qiang Wang, Huarong Zhou, Xiaomei Zhong*, Yuping Ning*. Sex-specific habenular dysconnectivity in patients with late-life depression. Transl Psychiatry. 2025,4;15(1):121.
39. Zhidai Xiao#, Ben Chen#, Mingfeng Yang, Qiang Wang, Danyan Xu, Gaohong Lin, Pengbo Gao, Shuang Liang, Qin Liu, Jiafu Li, Xiaomin Zheng*, Xiaomei Zhong*, Yuping Ning Abnormal functional network connectivity mediates the relationship between depressive symptoms and cognitive decline in late-onset depression. Psychological Medicine, 2025.8:55:e227
40. Nannan Pan#, Penghui Cao#, Ben Chen#, Li Chen, Xuezhen Liao, Yuping Ning. CX3CR1-TLR4 Axis as a Shared Neuroimmune Target in COVID-19 and Epilepsy: Integrative Transcriptomics and Gabapentin Repositioning. Biomedicines. 2025. 31;13(9):2133.
41. Xiaomin Zheng#, Ben Chen#, Mingfeng Yang#, Shuang Liang, Zhidai Xiao, Danyan Xu, Haoye Tan, Qiang Wang, Qin Liu, Jiafu Li, Pengbo Gao, Xiaomei Zhong*, Yuping Ning*. Sex Differences Emerge in Brain Activity and Connectivity in Late-Life Depression. Psychoradiology, 2025, 6:kkaf029
42. Ben Chen#, Shuang Liang#, Ting Su#, Youxuan Zheng, Wei He, Huarong Zhou, Qiang Wang, Mingfeng Yang, Gaohong Lin, Danyan Xu, Yunheng Chen, Jiafu Li, Qin Liu, Kexin Yao, Zhangying Wu, Min Zhang, Le Hou, Yueyang Zhang, Xiaomei Zhong* Yuping Ning*. Altered dynamic functional connectivity of orbitofrontal cortex underlies olfactory and cognitive impairment in late-life depression. 2026; 6:kkag002
43. Zihan Wang#, Ben Chen#, Danyan Xu#,Kexin Zhu, Jiayu Chen, Shihan Tian, Qiang Wang, Haoye Tan, Shuang Liang, Zhidai Xiao, Yujing Gan, Gaohong Lin, Mingfeng Yang, Yijie Zeng, Kexin Yao, Yicheng Lin, Qin Liu, Jiafu Li, Yunheng Chen, Xinming Rao, Yuping Ning*,Xiaomei Zhong*. Plasma metabolomics identifies lipid mediators linking depression and cognitive decline in late-life depression. J Affect Disord. 2026 1:121094.
44. Xuanzi Li#, Xiangzhu Zeng#, Jiafu Li#, Youxuan Zheng, Shihan Tian, Zihan Wang, Chiyuan Ma,Yicheng Lin, Gaohong Lin, Yijie Zeng, Zhidai Xiao, Haoye Tan, Mingfeng Yang, Shuang Liang, Zerui Liu, Pengbo Gao, Qianheng Wang, Hanna Lu, Xiaomei Zhong*, Ben Chen*, Yuping Ning*. Altered temporal dynamics of intrinsic brain activity in mild cognitive impairment with olfactory dysfunction. J Alzheimers Dis. 2026:13872877261431797.
45. Pengbo Gao#, Ben Chen#, Danyan Xu, Qiang Wang, Mingfeng Yang, Goahong Lin, Huarong Zhou, Xinxiao Huang, Yijie Zeng, Shuang Liang, Jiafu Li, Qin Liu, Kexin Yao, Zhidai Xiao, Xiaomei Zhong*, Yuping Ning*. Differential effects of PSEN1 mutations (p.P117L with ataxia and p.P264L without ataxia) in early-onset Alzheimer's disease. J Alzheimers Dis. 2026:13872877261430771.
46. Qin Liu#, Ben Chen#, Ting Su, Qiang Wang, Danyan Xu, Mingfeng Yang, Gaohong Lin, Yijie Zeng, Jingyi Lao, Shuang Liang, Jiafu Li, Kexin Yao, Zhidai Xiao, Pengbo Gao, Xiaomin Zheng, Xiaomei Zhong*, Yuping Ning*. Sex-Specific regional brain activity and cognitive function in mild cognitive impairment: An rs-fMRI study. Transl Psychiatry. 2026 Apr 6. doi: 10.1038/s41398-026-03985-9
47. Mingfeng Yang#, Ben Chen#, Qiang Wang#, Shuang Liang, Zhidai Xiao, Haoye Tan, Yujing Gan, Xiaomei Zhong*, Yuping Ning*. Elevated free water of white matter is associated with depressive symptoms and cognitive impairment in late-life depression independent of Alzheimer's pathology: a multi-shell diffusion MRI study. Psychological Medicine, 2026,accepted.
48. Ben Chen#, Pengbo Gao#, Huanmin Liu#, Danyan Xu, Qiang Wang, Mingfeng Yang, Haoye Tan, Zhidai Xiao, Shihan Tian, Zihan Wang, Youxuan Zheng, Xiaomin Zheng, Shuang Liang, Qin Liu, Jiafu Li, Xiaomei Zhong*, Yuping Ning*. Olfactory Radiomics Signatures Link pTau217 to Cognitive Impairment in Probable Alzheimer's Disease: A Multi- Cohort Machine Learning Study. Alzheimer's Research & Therapy, 2026, 24;18(1):140.
49. Shihan Tian#, Gaohong Lin#, Yijie Zeng#, Qiang Wang, Yicheng Lin, Kexin Yao, Zihan Wang, Zhidai Xiao, Jiayu Chen, Youxuan Zheng, Haoye Tan, Zhangying Wu, Mingfeng Yang, Danyan Xu, Xuanzi Li, Jingyi Lao, Shuang Liang, Yunheng Chen, Qin Liu, Jiafu Li, Yujing Gan, Mingyong Zeng, Ben Chen*, Yuping Ning*, Xiaomei Zhong*. A Multifeature Machine Learning and Resting-State EEG Study Reveals Differences in Beta Oscillation in Late-Life Depression With or Without Mild Cognitive Impairment， BMC Psychiatry，2026 7;26(1):502
50. Qiang Wang#, Ben Chen#, Qixuan Chen#, Zhidai Xiao, Mingyong Zeng, Pengbo Gao, Shuang Liang, Qin Liu, Kexin Yao, Mingfeng Yang, Haoye Tan, Gaohong Lin, Zhangying Wu, Danyan Xu, Haishan Shi, Min Zhang, Huanmin Liu, Yijie Zeng, Yicheng Lin, Shuwei Zhang, Cong Ouyang, Shihan Tian, Yujing Gan, Jieqin Lv, Xiang Liang, Yuwang Cheng, Jianwen Guo, Pengcheng Ran, Huarong Zhou, Xiaomei Zhong *, Yuping Ning*...Structural and diffusion MRI markers of the choroid plexus and perivascular regions are associated with Alzheimer’s disease pathology and cognition. Alzheimer's Research & Therapy
授权及申请专利
1. 授权发明专利“一种鼻后嗅觉测试的嗅笔”，专利号 ZL 2020 1 0997367.0，2023.05.26。
2. 授权发明专利“一种基于橡皮球的鼻后嗅觉测试方法及康复训练方法”，专利号 ZL 2020 1 1238783.9，2025.01.10。
3. 实用新型“一种鼻后嗅觉测试瓶”，专利号 ZL2020 2 2079959.2，2021.06.15。
4. 实用新型“一种用于鼻后嗅觉测试及康复训练的橡皮球”，专利号 ZL 2020 2 2565121.4，2021.08.03。
5. 实用新型“一种用于嗅觉识别测试的多腔嗅瓶”，专利号 ZL 2022 2 0473490.7，2022.09.02。
6. 实用新型“一种用于嗅觉训练的四腔嗅笔”，专利号 ZL 202220473127.5，2022.03.07。
7. 发明专利申请“一种用于阿尔茨海默病分析的计算机辅助诊断方法和系统”，申请号 2025115115839，2025.10.22。
8. 发明专利申请“一种基于增强现实的嗅觉功能自动化评估系统及方法”，申请号 2025115687753，2025.10.30。
主要荣誉与奖励
· 2026年广州医科大学精神卫生学院优秀教师
· 2025年度创新广州科技进步奖一等奖：老年痴呆血液及脑机接口电生理标记物诊断体系研发与应用。
· 2025年度广州市重大临床医疗成果二等奖：基于血浆标志物与多模态脑机接口的阿尔茨海默病早期诊疗体系研发与应用。
· 广东省生物医学工程科学技术奖二等奖：基于血浆标志物与多模态脑机接口的阿尔茨海默病早期诊疗体系研发与应用。
· 2025年度广东省测量控制技术与装备应用促进会科学技术奖技术创新奖特等奖：老年痴呆血液及脑机接口电生理标记物诊断体系研发与应用。
· 2025年第七届广东省医院协会医院管理技术创新项目科技创新类三等奖：基于中国人群的血浆 p-tau217 及 p-tau217/Aβ42 诊断阿尔茨海默症的标准阈值构建验证与临床转化研究。
· 2024年中国医师协会精神科医师分会“青年精神科医师希望之星”。
· 2024年广州市卫生健康委员会优秀人才。
· 2021年广东省科技进步奖二等奖：阿尔茨海默病早期预警与诊断系统研发及应用。
· 2021年中国仪器仪表学会科学技术进步二等奖：阿尔茨海默病早期预警与诊断系统研发及应用。
学术任职
· 《Journal of Alzheimer's Disease》编委。
· Frontier in Neurology 客座编辑。
· 《Psychoradiology》Associate Editor 与青年编委。
· 广东省健康科普促进会精神心理健康分会副主任委员。
· 广东省精准医学应用学会脑机接口分会常务委员。
· 广东省保健协会睡眠与心理分会常务委员。
· 广东省基层医药学会精神心理健康专委会常务委员。
· 广州市医师协会老年病科医师分会委员。
教学与学生培养
· 指导2024–2025学年度广州医科大学校级大学生创新创业训练计划项目“移动端数字化认知训练对大学生主观认知能力下降及伴随情绪症状改善作用研究”。
· 指导2022–2023年度大学生科技创新项目“内嗅皮层功能增强在减轻主观认知下降人群的气味识别受损中的 fMRI 研究”。
· 参与指导2025年广州医科大学第十五届“挑战杯”大学生创业计划竞赛项目“脑心动车：移动式智能脑健康服务系统”，获铜奖。
