【个人简介】
艾思志,医学博士,毕业于北京大学医学部,在香港中文大学精神病学系完成博士后训练,现为广州医科大学南山学者教授/博士生导师、广州医科大学附属脑科医院精神神经科学研究所副所长/睡眠医学研究室主任
【研究方向】
失眠障碍的发病机制及其干预策略研究
【科研项目】
1.国家自然科学基金,蓝斑去甲肾上腺素能神经元调控慢波活动在失眠加重心衰进展中的作用机制,2025.01-2028.12,项目批准号:82471506,49万元,在研,主持
2.国家科技部,国家重点研发计划,失眠障碍的认知调控及非药物干预手段开发,2022.01-2024.12,项目号:2021YFC2501503,480.00万元,在研,主持
3.国家自然科学基金-河南联合基金,睡眠过程中声音闭环刺激对恐惧记忆消退的影响及其神经机制研究,2020.01-2022.12,项目号 U1904159,48万元,已结题,主持
4.国家自然科学基金青年项目,声音闭环刺激在心衰合并失眠者自主神经功能调控中的作用,2019.01-2021.12,项目号 81801315,21万元,已结题,主持
5.中国科协,第七届中国科协青年托举人才项目, 2021.01-2023.12,项目号YESS20210242,在研,主持
6.广东省自然科学基金面上项目,REV-ERBa/IRS1/PI3K信号通路介导心肌胰岛素抵抗在失眠加重心衰进展中的作用机制,2023.01-2026.12,项目号2024A1515012967,15万,在研,主持
7.河南省科技厅——河南省高层次人才国际化培训项目,已结题,主持
8.河南省卫健委——科技英才海外研修工程项目 “声音闭环神经环刺激在心衰 患者失眠干预中的作用”,项目编号 2018076,已结题,主持
9.河南省卫健委——闭环迷走神经刺激在急性心梗患者 PCI 术后心肌保护中的 作用,项目编号 20180762018020363,已结题,主持
【代表性论文及著作】
近五年5篇代表作
1.Ai S*, Zhang J#, Zhao G, Wang N, Li G, So HC, Liu Y, Chau S, Chen J, Tan X, Jia F, Tang X, Shi J, Lu L, Wing YK. Causal associations of short and long sleep durations with 12 cardiovascular diseases: linear and nonlinear Mendelian randomization analyses in UK Biobank. Eur Heart J. 2021 Sep 7;42(34):3349-3357. (IF = 39.3, 中科院1区)
2.Ai S*#, Ye S, Li G, Leng Y, Stone KL, Zhang M, Wing Y, Zhang J, Liang Y#. Association of Disrupted Delta Wave Activity During Sleep With Long-Term Cardiovascular Disease and Mortality. J Am Coll Cardiol. 2024 Apr 30;83(17):1671-1684. doi: 10.1016/j.jacc.2024.02.
040. (IF = 21.7, 中科院1区)
3. Liang YY*, Zhou M, He Y, Zhang W, Wu Q, Luo T, Zhang J, Jia F, Qi L#, Ai S#, Zhang J#. Observational and genetic evidence disagree on the association between loneliness and risk of multiple diseases. Nat Hum Behav. 2024 Sep 16. doi: 10.1038/s41562-024-01970-0. (IF = 21.4,中科院1区)
4. Feng H*, Yang L*, Ai S*, Liu Y, Zhang W, Lei B, Chen J, Liu Y, Chan JWY, Chan NY, Tan X, Wang N, Benedict C, Jia F, Wing YK, Zhang J#. Association between accelerometer-measured amplitude of rest-activity rhythm and future health risk: a prospective cohort study of the UK Biobank. Lancet Healthy Longev. 2023 May;4(5): e200-e210. (IF = 13.1,中科院1区)
5. Ai S*, Li Z*, Wang S, Zhao Y, Chen S, Chan W, Au C, Bao Y, Li A, Zhang J, Chan C#, Wing YK#. Blood pressure and childhood obstructive sleep apnea: a systematic review and meta-analysis. Sleep Med Rev. 2022. Oct;65:101663. (IF = 10.5,中科院1区)
近五年其他10篇代表作
1. Zheng J*, Ai S*, Chang SH, Meng SQ, Shi L, Deng JH, Di TQ, Liu WY, Chang XW, Yue JL, Yang XQ, Zeng N, Bao YP, Sun Y#, Lu L#, Shi J#. Association between alcohol consumption and sleep traits: observational and mendelian randomization studies in the UK biobank. Mol Psychiatry. 2024 Mar;29(3):838-846. doi: 10.1038/s41380-023-02375-7. (IF = 9.6,中科院1区)
2. Ai S*, Wang X*, Wang S, Zhao Y, Guo S, Li GH, Chen Z, Lin F, Li Y, Zhang J#, Zhao G#. Effects of glycemic traits on left ventricular structure and function: a two-sample Mendelian randomization study. Cardiovasc Diabetol. 2022 Jun 17;21(1):109. (IF = 9.3,中科院1区)
3.Yang L*, Feng H*, Ai S*, Liu Y, Lei B, Chen J, Tan X, Benedict C, Wang N, Wing YK, Qi L#, Zhang J#. Association of accelerometer-derived circadian abnormalities and genetic risk with incidence of atrial fibrillation. NPJ Digit Med. 2023 Mar 4;6(1):31. doi: 10.1038/s41746-023-00781-3. (IF =15.2,中科院1区)
4.Ai S*, Yin Y*, Chen Y, Tang X, Lu L, Zhu L#, Shi J#. Promoting subjective preferences in simple economic choices during sleep. Elife, 2018 Dec 6;7:e40583. (IF = 7.7,中科院1区)
5.Liang Y*, Ai S*, Xue H, Chen Y, Zhou J, Shu X, Weng F, Zhou M, Ma H, Zhang J, Geng Q#, Wing YK#. Joint Associations of Device-measured Sleep Duration and Efficiency with All-cause and Cause-specific Mortality: A Prospective Cohort Study of 90 398 UK Biobank Participants. J Gerontol A Biol Sci Med Sci. 2023 Apr 26: glad108. doi: 10.1093/gerona/glad108. (IF=5.1,中科院1区)
6. Wang X*, Zhao C, Feng H, Li G, He L, Yang L, Liang Y, Tan X, Xu Y, Cui R, Sun Y, Guo S, Zhao G, Zhang J#, Ai S#. Associations of insomnia with insulin resistance traits: a cross-sectional and Mendelian Randomization study. J Clin Endocrinol Metab. 2023 Feb 16: dgad089. doi: 10.1210/clinem/dgad089.(IF =5.8,中科院2区)
7. Liang Y*, Chen J, Peng M, Zhou J, Chen X, Tan X, Wang N, Ma H, Guo L, Zhang J, Wing YK, Geng Q#, Ai S#. Association between sleep duration and metabolic syndrome: linear and nonlinear Mendelian randomization analyses. J Transl Med. 2023 Feb 7;21(1):90. doi: 10.1186/s12967-023-03920-2. (IF =7.4,中科院2区)
8.Feng H*, Yang L*, Liang YY*#, Ai S, Liu Y, Liu Y, Jin X, Lei B, Wang J, Zheng N, Chen X, Chan JWY, Sum RKW, Chan NY, Tan X, Benedict C, Wing YK, Zhang J#. Associations of timing of physical activity with all-cause and cause-specific mortality in a prospective cohort study. Nat Commun. 2023 Feb 18;14(1):930. doi: 10.1038/s41467-023-36546-5. (IF=16.6,中科院1区)
9.Liang Y*, Chen Y*, Feng H, Liu X, Ai QH, Xue H, Shu X, Weng F, He Z, Ma J, Ma H, Ai S, Geng Q#, Zhang J#. Association of Social Isolation and Loneliness With Incident Heart Failure in a Population-Based Cohort Study. JACC Heart Fail. 2023 Mar;11(3):334-344. doi: 10.1016/j.jchf.2022.11.028. (IF=13.0,中科院1区)
10.Liang Y*, He Y*, Huang P, Feng H, Li H, Ai S, Du J, Xue H, Liu Y, Zhang J, Qi L#, Zhang J#. Accelerometer-measured physical activity, sedentary behavior, and incidence of macrovascular and microvascular events in individuals with type 2 diabetes mellitus and prediabetes. J Sport Health Sci. 2024 Aug 29:100973. doi: 10.1016/j.jshs.2024.100973. (IF=9.7,中科院1区)
【所获荣誉和奖励】
荣誉称号
1.2024 年度荣获中国睡眠研究会第十六届全国学术年会优秀论文
2.2022年荣获中国科协“青年托举人才”项目
3.2021年度荣获第三届“中青年心血管病学菁英”临床科研创新奖
4.2021年度荣获中国睡眠研究会第十三届全国学术年会优秀论文
5.2021年度荣获第三届亚洲睡眠医学会“青年科学家”奖
学术兼职
1.中国睡眠研究会 理事
2.中华医学会精神医学分会睡眠障碍研究协作组 委员
3.中国睡眠研究会青年工作委员会 副主任委员
4.美国心脏病学会 Fellow in Training 成员
5.Depression and Anxiety编委
6.Brain-Apparatus Communication编委
7.BMJ、Circulation等20余个SCI杂志审稿人
8.中国睡眠研究会睡眠与心理卫生专业委员会 常务委员
9.海峡两岸医药卫生交流协会睡眠医学专业委员会 委员