
【个人简介】
艾思志,医学博士,毕业于北京大学,香港中文大学博士后。现任广州医科大学南山学者教授/博导,精神神经科学研究所副所长/睡眠医学研究室主任。入选国家高层次人才青年项目、中国科协青年托举人才、广东省杰出青年基金获得者。目前担任中国睡眠研究会理事、中国睡眠研究会青年工作委员会副主任委员等学术兼职。
【研究方向】
失眠障碍的发病机制及其非药物干预策略开发
【科研项目】
1. 脑科学与类脑研究国家科技重大专项, 沉浸式诱发与多模态数据融合驱动的认知情绪异常精确评估方法研究,2026-8-30至2030-12-31,990万,在研,主持;
2. 国家高层次人才青年项目,2025-9-30至2028-9-30,在研,主持;
3. 国家重点研发计划重点专项,失眠障碍的认知调控及非药物干预手段开发,2022-01-31至2024-12-31,480万,结题,主持;
4. 广东省基础与应用基础研究自然科学基金-杰出青年项目,睡眠障碍诱发心脑血管疾病的机制及干预研究,2025-01-31至2028-01-31,100万,在研,主持;
5. 国家自然基金面上项目,蓝斑去甲肾上腺素能神经元调控慢波活动在失眠加重心衰进展中的作用机制,2025-01-31至2028-12-31,49万,在研,主持
【代表性论文及著作】
1. Ai S*, Zhang J#, Zhao G, Wang N, Li G, So HC, Liu Y, Chau SWH, Chen J, Tan X, Jia F, Tang X, Shi J, Lu L, Wing YK. Causal associations of short and long sleep durations with 12 cardiovascular diseases: linear and nonlinear Mendelian randomization analyses in UK Biobank. Eur Heart J. 2021 Sep 7;42(34):3349-3357. (IF = 45.6,中科院1区);
2. Ai S*#, Ye S, Li G, Leng Y, Stone KL, Zhang M, Wing YK, Zhang J, Liang Y#. Association of disrupted delta wave activity during sleep with long-term cardiovascular disease and mortality. J Am Coll Cardiol. 2024 Apr 30;83(17):1671-1684. (IF = 22.3,中科院1区);
3. Ma Z*, Cao F*, Liao M*, Min R, Zheng R, Sun X, Chen X, Gong Y#, Ai S#, Kang X#. Cardiovascular adverse events associated with epidermal growth factor receptor tyrosine kinase inhibitors in EGFR-mutated non-small cell lung cancer: systematic review and network meta-analysis. BMJ. 2025 Sep 2;390:e082834. (IF = 55.1,中科院1区);
4. Yang L*, Feng H*, Ai S*, Liu Y, Lei B, Chen J, Tan X, Benedict C, Wang N, Wing YK, Qi L#, Zhang J#. Association of accelerometer-derived circadian abnormalities and genetic risk with incidence of atrial fibrillation. NPJ Digit Med. 2023 Mar 4;6:31. (IF = 18.0,中科院1区);
5. Liang Y*, Zhou M*, He Y*, Zhang W, Wu Q, Luo T, Zhang J, Jia F, Qi L#, Ai S#, Zhang J#. Observational and genetic evidence disagree on the association between loneliness and risk of multiple diseases. Nat Hum Behav. 2024 Nov;8(11):2209-2221. (IF = 17.5,中科院1区);
6. Feng H*, Yang L*, Ai S*, Liu Y, Zhang W, Lei B, Chen J, Liu Y, Chan JWY, Chan NY, Tan X, Wang N, Benedict C, Jia F, Wing YK, Zhang J#. Association between accelerometer-measured amplitude of rest-activity rhythm and future health risk: a prospective cohort study of the UK Biobank. Lancet Healthy Longev. 2023 May;4(5):e200-e210. (IF = 20.5,中科院1区);
7. Ai S*, Li Z*, Wang S, Chen S, Chan JW, Au CT, Bao Y, Li AM, Zhang J, Chan KCC#, Wing YK#. Blood pressure and childhood obstructive sleep apnea: a systematic review and meta-analysis. Sleep Med Rev. 2022 Oct;65:101663. (IF = 11.6,中科院1区);
8. Zheng JW*, Ai S*, Chang SH, Meng SQ, Shi L, Deng JH, Di TQ, Liu WY, Chang XW, Yue JL, Yang XQ, Zeng N, Bao YP, Sun Y#, Lu L#, Shi J#. Association between alcohol consumption and sleep traits: observational and Mendelian randomization studies in the UK Biobank. Mol Psychiatry. 2024 Mar;29(3):838-846. (IF = 10.4,中科院1区);
9. Weng B*, Wei J, Chen H, Zhao Y, Wang N, Feng H, Ai S#, Tan X#. Large-scale plasma proteomics for predicting future cardiovascular and all-cause mortality among individuals with cardiovascular-kidney-metabolic syndrome stage 0-3. Metabolism. 2026 Jun;179:156600. (IF = 16.7,中科院1区);
10. Ai S*, Wu Q*, Nie Y*, Ou Y, He Y, Li P, Ai QYH, Feng H, Liu Y, Luo T#, Zhang J#, Liang Y#. Social isolation and 59 common health conditions: insights from observational and genetics analyses. BMC Med. 2026;24:282. (IF = 8.7,中科院1区)
【所获荣誉和奖励】
1. 2026年荣获广东省科技进步二等奖(第3完成人);
2. 2026年荣获广州市科技创新菁英奖(个人奖);
3. 2026年荣获龚兰生青年学者一等奖(个人奖);
4. 2025年入选国家高层次人才青年项目;
5. 2025年荣获世界睡眠大会“新研究者奖”;
6. 2025年荣获第十二届东方新星提名奖;
7. 2021年荣获亚洲睡眠医学会“青年科学家奖”;
8. 2024年广东省“杰出青年基金”获得者;
9. 2024年广州市高层次人才;
10. 2023年广州市卫健委优秀人才