【梁燕个人简介】

l广州医科大学南山学者特聘教授、博士研究生导师、博士后合作导师

l广州医科大学附属脑科医院，精神神经科学研究所副所长, 中国老年学和老年医学学会脑认知与健康分会常务委员，国际心身医学学会（ICPM）会员，JCBP杂志青年编委

【研究方向】

l神经病学；研究聚焦心理应激对心身疾病的作用及机制

【科研项目】

1.国家自然科学基金青年项目； mPFC-杏仁核环路介导交感神经亢进在心理应激诱发心肌缺血中的作用及机制研究； 2022-01至2024-12，30万，在研，主持。

2.广州市科技局校（院）企联合资助项目；社交孤立诱发心肌缺血的神经环路机制研究；2024.04至2026.03，在研，主持。

3.中国博士后科学基金第70批面上项目；情绪加工环路介导交感神经亢进所致心理应激诱发心肌缺血的神经影像机制研究；2021.01至2023.12，结题，主持。

4.广东省医学科学技术研究基金；脑小血管病相关抑郁的脑网络拓扑结构异常与失耦合机制研究；2020.7至2022.6，结题，主持。

5.中央高校基本科研业务费专项资金资助；血管损伤介导的脑网络机制在调控卒中后同情心缺乏的发病和转归中的作用：1年纵向多模态影像研究；2019.01至2021.12，结题，主持。

【代表性论文及著作】（近3年）

<2024>

Liang YY^#, Zhou M^#, He Y^#, Zhang W, Wu q, Luo T, Zhang J, Jia F, Qi L^*, Ai S^*, Zhang J^*. Observational and genetic evidence disagree on the association between loneliness and risk of multiple diseases. Nat Hum Behav. 2024 July 24; Accepted.[IF = 21.4]

Ai S^#, Ye S, Li G, Leng Y, Stone KL, Zhang M, Wing YK, Zhang J, Liang YY^*. Association of disrupted delta wave activity during sleep with long-term cardiovascular disease and mortality. J Am Coll Cardiol. 2024 Apr 30;83(17):1671-1684. [IF = 21.4]

Liang YY^#, He Y^#, Huang P, Feng H, Li H, Ai S, Du J, Xue H, Liu Y, Zhang J, Qi L^*, Zhang J^*. Accelerometer-measured physical activity, sedentary behavior, and incidence of macrovascular and microvascular events in individuals with type 2 diabetes mellitus and prediabetes. J Sport Health Sci. 2024 Aug 29:100973.[IF = 9.7]

Liu Y^#, Feng H^#, Du J, Yang L, Xue H, Zhang J, Liang YY^*, Liu Y^*. Associations between accelerometer-measured circadian rest-activity rhythm, brain structural and genetic mechanisms, and dementia. Psychiatry Clin Neurosci. 2024 Apr 27. Online ahead of print. [IF = 11.9]

Chen Y^#, Xue H^#, Nie Y, Zhou Y, Ai S, Liu Y, Zhang J, Liang YY^*. Evaluation of changes in social isolation and loneliness with incident cardiovascular events and mortality. J Epidemiol Glob Health. Accept. [IF = 7.3]

Chen Y^#, Xue H^#, Ai S, Liu Y, Nie Y, Ai QH, Zhang J, Liang YY^*. Trajectories of social isolation and loneliness and the risk of incident type 2 diabetes mellitus across genetic risk score. Diabetes Metab. 2024 Mar 6;50(3):101526. [IF = 7.2]

<2023>

Liang YY^#, Chen Y^#, Feng H, Liu X, Ai QH, Xue H, Shu X, Weng F, He Z, Ma J, Ma H, Ai S, Geng Q^*, Zhang J^*. Association of social isolation and loneliness with incident heart failure in a population-based cohort study. JACC Heart Fail. 2023 Mar;11(3):334-344. [IF = 10.3]

Liang YY, Chen Y, Feng H, Xue H, Nie Y, Ai QH, Ma J, Yang L, Zhang J, Ai S^*. Social isolation, loneliness and subsequent risk of major adverse cardiovascular events among individuals with type 2 diabetes mellitus. Gen Psychiatr. 2023 Dec 27;36(6):e101153. [IF = 11.9]

Feng H^#, Yang L^#, Liang YY^#*, Ai S, Liu Y, Liu Y, Jin X, Lei B, Wang J, Zheng N, Chen X, Chan JWY, Sum RKW, Chan NY, Tan X, Benedict C, Wing YK, Zhang J^*. Associations of timing of physical activity with all-cause and cause-specific mortality in a prospective cohort study. Nat Commun. 2023 Feb 18;14(1):930. [IF =14.7]

Jin X^#, Chen Y^#, Feng H^#, Zhou M, Chan JWY, Liu Y, Kong APS, Tan X, Wing YK, Liang YY^*, Zhang J^*. Association of accelerometer-measured sleep duration and different intensities of physical activity with incident type 2 diabetes in a population-based cohort study. J Sport Health Sci. 2023 Mar 3;13(2):222-232. [IF = 9.7]

Liang YY^#, Feng H^#, Chen Y, Jin X, Xue H, Zhou M, Ma H, Ai S, Wing YK, Geng Q^*, Zhang J^*. Joint association of physical activity and sleep duration with risk of all-cause and cause-specific mortality: a population-based cohort study using accelerometry. Eur J Prev Cardiol. 2023 Jul 12;30(9):832-843. [IF = 8.3]

Liang YY, Chen J, Peng M, Zhou J, Chen X, Tan X, Wang N, Ma H, Guo L, Zhang J, Wing YK, Geng Q^*, Ai S^*. Association between sleep duration and metabolic syndrome: linear and nonlinear Mendelian randomization analyses. J Transl Med. 2023 Feb 7;21(1):90. [IF = 7.4]

Liang YY^#, Ai S^#, Xue H, Chen Y, Zhou J, Shu X, Weng F, Zhou M, Ma H, Zhang J, Geng Q^*, Wing YK. Joint associations of device-measured sleep duration and efficiency with all-cause and cause-specific mortality: a prospective cohort study of 90 398 UK Biobank participants. J Gerontol A Biol Sci Med Sci. 2023 Aug 27;78(9):1717-1724. [IF = 5.1]

<2022>

Liang YY^#, Ai S^#, Weng F, Feng H, Yang L, He Z, Xue H, Zhou M, Shu X, Chen Y, Ma H, Guo L, Geng Q^*, Zhang J^*. Associations of childhood maltreatment and genetic risks with incident heart failure in later life. J Am Heart Assoc. 2022 Oct 18;11(20):e026536. [IF = 5.4]

Chen Y^#, Yang L^#, Liang YY^#, He Z, Ai QH, Chen W, Xue H, Zhou M, Wang Y, Ma H, Geng Q^*. Interaction of night shift work with polymorphism in melatonin receptor 1B gene on incident stroke. Scand J Work Environ Health. 2022 Jul 1;48(5):372-379. [IF = 6.3]

【所获荣誉和奖励】

1.Travel Grant Award，EPA 2024论坛交流主持人，第32届欧洲精神病学年会(European Congress of Psychiatry)，2024.04，匈牙利布达佩斯

2.高质量论文奖，中华医学会第29届心身医学分会年会，中国昆明

3.特邀演讲嘉宾，2011.10，中华医学会第27届心身医学分会年会，中国太原

4.Travel Grant Award，欧洲卒中年会（European Stroke Conference），2017.05，德国柏林

5.特邀演讲嘉宾，2017.11，中华医学会第23届心身医学分会年会，中国南京