研究生院

许万福
更新时间:2023-03-19


许万福,男,出生于1987年3月,研究主管,副研究员,硕士研究生导师,广州市高层次青年后备人才。发表SCI文章32篇,其中一作/共6篇,并列通讯8篇,5分上共计12篇SCI,共主持国家、省市级课题9项,主要从事儿童消化系统疾病及病毒性肠炎,指导临床医生申报并立项课题8项,已协助指导3学术型研究生和3名临床在职博士毕业。

主要研究方向:1. 能量代谢与胃肠道疾病发病机制; 2.临床基因突变患者的致病机制及治疗研究。

代表作

1. Xu W, Zhang Z, Zou K, Cheng Y, Yang M, Chen H, et al. MiR-1 suppresses tumor cell proliferation in colorectal cancer by inhibition of Smad3-mediated tumor glycolysis. Cell Death Dis 2017, 8(5): e2761.

2. Xu W, He L, Xia Q, Jia C, Geng L, Yang M, et al. A far-red-emissive AIE active fluorescent probe with large stokes shift for detection of inflammatory bowel disease in vivo. J Mater Chem B 2018, 6(5): 809-815.

3. Zhang S, Xu W, Wang H, Cao M, Li M, Zhao J, et al. Inhibition of CREB-mediated ZO-1 and activation of NF-kappaB-induced IL-6 by colonic epithelial MCT4 destroys intestinal barrier function. Cell Prolif 2019, 52(6): e12673.

4. Xu W, Qian J, Zeng F, Li S, Guo W, Chen L, et al. Protein kinase Ds promote tumor angiogenesis through mast cell recruitment and expression of angiogenic factors in prostate cancer microenvironment. J Exp Clin Cancer Res 2019, 38(1): 114.

5. Xu W, Zeng F, Li S, Li G, Lai X, Wang QJ, et al. Crosstalk of protein kinase C epsilon with Smad2/3 promotes tumor cell proliferation in prostate cancer cells by enhancing aerobic glycolysis. Cell Mol Life Sci 2018, 75(24): 4583-4598.

6. Liu M, Xu W, Su M, Fan P. REC8 suppresses tumor angiogenesis by inhibition of NF-kappaB-mediated vascular endothelial growth factor expression in gastric cancer cells. Biol Res 2020, 53(1): 41.

7. Li M, Zhao J, Cao M, Liu R, Chen G, Li S, et al. Mast cells-derived MiR-223 destroys intestinal barrier function by inhibition of CLDN8 expression in intestinal epithelial cells. Biol Res 2020, 53(1): 12.

8. Chen P, Li L, Wang H, Zhao J, Cheng Y, Xie J, et al. Omeprazole, an inhibitor of proton pump, suppresses De novo lipogenesis in gastric epithelial cells. Biomed Pharmacother 2020, 130: 110472.

9. Wang Y, Zhou X, Zou K, Chen G, Huang L, Yang F, et al. Monocarboxylate Transporter 4 Triggered Cell Pyroptosis to Aggravate Intestinal Inflammation in Inflammatory Bowel Disease. Front Immunol 2021, 12: 644862.

10. Xie J, Fan L, Xiong L, Chen P, Wang H, Chen H, et al. Rabeprazole inhibits inflammatory reaction by inhibition of cell pyroptosis in gastric epithelial cells. BMC Pharmacol Toxicol 2021, 22(1): 44.

11. Zhou Y, Chen S, Yang F, Zhang Y, Xiong L, Zhao J, et al. Rabeprazole suppresses cell proliferation in gastric epithelial cells by targeting STAT3-mediated glycolysis. Biochem Pharmacol 2021, 188: 114525.

12. Zhang S, Pan W, Wang H, Zhi C, Lin Y, Wu P, et al. Vitronectin, a Novel Urinary Proteomic Biomarker, Promotes Cell Pyroptosis in Juvenile Systemic Lupus Erythematosus. Mediators Inflamm 2022, 2022: 8447675.

13. Cao M, Peng B, Chen H, Yang M, Chen P, Ye L, et al. miR-34a induces neutrophil apoptosis by regulating Cdc42-WASP-Arp2/3 pathway-mediated F-actin remodeling and ROS production. Redox Rep 2022, 27(1): 167-175.


 
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