【个人简介】
外科学博士,2011年毕业于中山医科大学,毕业后一直在广州医科大学附属妇女儿童医疗中心,从事小儿外科专业10余年,擅长儿童神经母细胞瘤、畸胎瘤、尤文肉瘤、肺部肿瘤、先天性肺囊性病变、肺隔离症、膈疝、食道裂孔疝,及鸡胸、漏斗胸等小儿外科疾病的微创手术;专注儿童恶性肿瘤特别是神经母细胞瘤的微创手术、化疗等综合治疗;致力于儿童肿瘤治疗新方案、新技术的研究与探索,并率先开展国内儿童肿瘤的胸腔热灌注治疗,已取得良好的疗效。同时注重儿童肿瘤微环境的基础研究与转化工作,研究成果在国内外期刊发表论文近20篇。
【研究方向】
小儿外科学;儿童实体肿瘤
【科研项目】
1.广州市卫生健康科技项目:2019-5-1至2022-4-30内源性VEGF调控PD-1/PD-L1促进神经母细胞瘤生长的作用及机制研究,3万,已结题,主持
2.广州市科技局基础研究计划一般项目:2022-5-1至2024-4-30,KHDRBS1激活NF-κB通路上调PD-L1表达促进神经母细胞瘤生长的作用及机制,5万,已结题,主持
【代表性论文及著作】
1. Tang J, Liu F, Huang D, et al. circ0125803 facilitates tumor progression by sponging miR-197-5p and upregulating E2F1 in neuroblastoma. Pathology, research and practice 2022; 233: 153857
2. Miao L, Zhuo Z, Tang J, et al. FABP4 deactivates NF-κB-IL1α pathway by ubiquitinating ATPB in tumor-associated macrophages and promotes neuroblastoma progression[J]. Clin Transl Med,2021,11(4):e395(并列第一)
3. Tang J, Zhang D, Xu YY, et al. Clinical characteristics and therapeutic outcomes of mediastinal neuroblastoma with intraspinal extension: a retrospective study. Translational pediatrics 2021; 10(4): 715-22.
4. Tang J, Lu H, Yang Z, et al. Associations between WTAP gene polymorphisms and neuroblastoma susceptibility in Chinese children. Translational pediatrics 2021; 10(1): 146-52
5. Lin A, Hua RX, Tang J, et al. KRAS rs7973450 A>G increases neuroblastoma risk in Chinese children: a four-center case-control study. OncoTargets and therapy 2019; 12: 7289-95.(并列第一)
6. Tang J, Liu W, Zhu J, et al. RSRC1 and CPZ gene polymorphisms with neuroblastoma susceptibility in Chinese children. Gene 2018; 662: 83-7.
7. Tang J, Qian Y, Zhu J, et al. Lack of associations between AURKA gene polymorphisms and neuroblastoma susceptibility in Chinese children. Bioscience reports 2018; 38(3).
8. Tang J, Zhang D, Liu W, Zeng JX, Yu JK, Gao Y. Differentiation between cystic biliary atresia and choledochal cyst: A retrospective analysis. Journal of paediatrics and child health 2018; 54(4): 383-9.