【个人简介】

周睿琼，医学博士，副研究员，主治医师，硕士研究生导师。2020年博士毕业于上海交通大学医学院，获妇产科学博士学位。2020年8月至今就职于广东省妇幼保健院生殖科，具备扎实的生殖医学临床研究与基础研究背景，在生殖内分泌、PCOS机制探索、辅助生殖技术临床优化等方面积累了丰富经验。主持国自然青年科学基金项目1项（已结题），广东省自然面上项目1项（在研）。近5年，以单独第一作者在生殖领域国际权威期刊发表14篇SCI论文，其中包括：《Human Reproduction open》、《Fertility and Sterility》等杂志。

教育经历：2005-9至2010-6，安徽医科大学，临床医学，学士；2011-9至2014-6，中南大学湘雅医学院，妇产科学，硕士；2017-9至2020-6，上海交通大学医学院，妇产科学，博士。

工作经历：2014.08至2015.10，海南省人民医院妇科，住院医师；2015.11至2017.08，深圳武警医院生殖科，主治医师；2020.08至今，广东省妇幼保健院生殖科，主治医师/副研究员。

【研究方向】

生殖医学/妇产科学

【科研项目】

1. 广东省自然科学基金面上项目，高雄相关AR-FOXO4环路调节失衡参与PCOS排卵障碍发生的机制研究，2025-01-01至2027-12-31，10万，在研，主持。

2. 国家自然科学基金青年科学基金项目，FOXO4调控颗粒细胞功能参与多囊卵巢综合征排卵障碍发生的机制研究，2022-01-01至2024-12-31，30万，结题，主持。

3. 北京健康促进会2023年度生殖医学中青年医生研究项目，冻胚移植激素替代周期中孕酮转化时间对D6囊胚移植活产率的影响——一项前瞻性随机对照研究，2023-12-01至2025-12-31，15万，结题，主持。

【代表性论文及著作】

1. Zhou R, Wang Z, Dong M, Wang S, Huang L, Wang J, Zhang X, Liu F. NR5A2 increases inflammation and cell proliferation by regulating the nuclear factor κB pathway in polyendocrine metabolic ovarian syndrome. Reprod Biomed Online. 2026 Jun 11;53(4):105821. (IF=3.9)

2. Zhou R, Wang Z, Zhu Z, Dong M, Wang J, Huang L, Qi Q, Zhang X, Liu F. Association between endogenous oxytocin levels and live birth rates following fresh embryo transfer: a prospective cohort study. Front Endocrinol (Lausanne). 2026 Jun 2;17:1850346. (IF=5.7)

3. Zhou R, Dong M, Wang Z, Huang L, Qi Q, Wang F, Xu L, Zhang X, Liu F. Interaction between progesterone exposure duration and blastocyst expansion stage on live birth following frozen-thawed transfer of day-6 blastocysts. Front Endocrinol (Lausanne). 2026 Apr 23;17:1813202. (IF=5.7)

4. Zhou R, Wang Z, Dong M, Huang L, Su N, Qi Q, Huang J, Wang F, Zhang X, Liu F. Effect of progesterone timing on live birth rates in day-6 blastocyst frozen-thawed embryo transfer cycles: a randomized controlled trial. Hum Reprod Open. 2026 Mar 16;2026(2):hoag023. (IF=11.1)

5. Zhou R, Zhu Z, Wang Z, Dong M, Huang L, Wang S, Zhang X, Liu F. Association between MTHFR polymorphisms and vitamin D status in infertile women: a mediation analysis. Front Nutr. 2025 Sep 11;12:1644302. (IF=5.1)

6. Zhou R, Wang Z, Dong M, Wang S, Li X, Huang J, Zhang X, Liu F. Hyperandrogen-induced imbalance of FOXO4-AR regulatory loop contributes to ovulatory disorders in polycystic ovary syndrome. Mol Ther Nucleic Acids. 2025 Apr 20;36(2):102543. (IF=6.1)

7. Zhou R, Dong M, Huang L, Wang S, Wang Z, Xu L, Zhang X, Liu F. Comparison of Cumulative Live Birth Rates Between Progestin and GnRH Analogues in Preimplantation Genetic Testing Cycles. J Clin Endocrinol Metab. 2025 Feb 18;110(3):611-623. (IF=5)

8. Zhou R, Zhu Z, Dong M, Wang Z, Huang L, Wang S, Zhang X, Liu F. Nonlinear correlation between serum vitamin D levels and the incidence of endometrial polyps in infertile women. Hum Reprod. 2024 Dec 1;39(12):2685-2692. (IF=6.0)

9. Zhou R, Dong M, Wang Z, Huang L, Wang S, Chen Y, Zhu Z, Zhang X, Liu F. Impact of different progesterone timings on live birth rates for blastocyst frozen embryo transfer cycles. Reprod Biomed Online. 2024 Oct;49(4):104307. (IF=3.7)

10. Zhou R, Dong M, Huang L, Zhu X, Wei J, Zhang Q, Liu D, Zhang X, Liu F. Association between serum LH levels on hCG trigger day and live birth rate after fresh embryo transfer with GnRH antagonist regimen in different populations. Front Endocrinol (Lausanne). 2023 Jul 5;14:1191827. (IF=5.2)

11. Zhou R, Dong M, Huang L, Wang S, Fan L, Liang X, Zhang X, Liu F. Comparison of cumulative live birth rates between progestin-primed ovarian stimulation protocol and gonadotropin-releasing hormone antagonist protocol in different populations. Front Endocrinol (Lausanne). 2023 Apr 18;14:1117513. ( IF=5.2)

12. Zhou R, Zhang X, Huang L, Wang S, Li L, Dong M, Zhu X, Liu F. The impact of different cycle regimens on birthweight of singletons in frozen-thawed embryo transfer cycles of ovulatory women. Fertil Steril. 2022 Mar;117(3):573-582. (IF=7.49)

13. Zhou R, Zhang X, Huang L, Zhu X, Dong M, Liu W, Wang S, Liu F. Association between serum estradiol levels prior to progesterone administration in artificial frozen-thawed blastocyst transfer cycles and live birth rate: a retrospective study. BJOG. 2021 Dec;128(13):2092-2100. (IF=7.331)

14. Zhou R, Zhang X, Dong M, Huang L, Zhu X, Wang S, Liu F. Association between endogenous LH level prior to progesterone administration and live birth rate in artificial frozen-thawed blastocyst transfer cycles of ovulatory women. Hum Reprod. 2021 Sep 18;36(10):2687-2696. (IF=6.353)