顾崇娟,女,1979年出生,妇产科学硕士研究生导师。博士毕业于四川大学华西医学中心,现为广州市妇女儿童医疗中心妇科门诊副主任医师。研究方向:妇科内分泌、生殖遗传。
从事妇产科临床、教学近二十年,硕士攻读生殖医学,博士攻读临床遗传学,对生殖内分泌及生殖遗传有较有较深入的研究。对女性全生命周期妇科内分泌疾病,不孕症,复发性流产等疾病诊治有丰富的经验。近年科研工作专注于女性生育力保护、多囊卵巢综合征的分子机制及复发性流产的遗传病因。主持或参与课题数项,发表国际期刊及国内核心杂志论文近10余篇,主译出版著作1部。
近五年主持的科研项目:
(1)广州市科学技术局, 基础研究, 202102010300, 绒毛外泌体在母胎界面免疫调控中的作用初探, 2021-04 至 2023-03, 30万元, 结题, 项目负责人
(2)广东省基础与应用基础基金委员会,基础研究,2023A1515220201,miR-654-3p调控UBN2影响滋养细胞功能增加自然流产的机制以及作为自然流产分子标志物的研究,2023-11至2026-10,10万元,在研,项目负责人
主要著作和论文:
(1)顾崇娟,温灿良,李 玲,李 茹,何耀娟,1514例自然流产绒毛染色体微阵列检测分析,《实用妇产科》2023年1月第39 卷第1期,61-66页
(2) Chongjuan Gu; Huan Gao; Kuanrong Li; Xinyu Dai; Zhao Yang; Ru Li; Canliang Wen; YaojuanHe ; Copy Number Variation Analysis of Euploid Pregnancy Loss, Frontiers in Genetics, 2022,13(766492): 1-10 (期刊论文)
(3) Chongjuan Gu; Yaojuan He; Xiaojun Li; Qingfeng Li; Qingshan Xuan; Kuanrong Li ; The
effects of first-trimester subchorionic hematoma on pregnancy outcomes: a retrospective cohort
study., Archives of Gynecology and Obstetrics, 2022, 9(14): 1-6 (期刊论文)
(4) Chongjuan Gu; Kuanrong Li; Ling Li; Huan Gao; Ru Li; Yaojuan He ; Genomic imbalance in
euploid pregnancy loss, Journal of Assisted Reproduction and Genetics, 2022, 39(9): 2115-
2124 (期刊论文)
(5)Chongjuan Gu; Xiaoqin Zeng; Quan Shi; Qing Xiao; Yaojuan He ; Androgen-secreting adult
granulosa cell tumor in a woman with polycystic ovary syndrome: a case report, Gynecological
Endocrinology, 2022, 38: 1014-1016 (期刊论文)
(6) Chongjuan Gu, Kuanrong Li, Ru Li, Ling Li, Xiaojun Li, Xinyu Dai and Yaojuan He*, Chromosomal Aneuploidy Associated With Clinical Characteristics of Pregnancy Loss Frontiers in Genetics, April 2021, Volume 12, Article 667697
(7) Chongjuan Gu, Hao Tan, Junbao Yang, Yilu Lu, Yongxin Ma*, Congenital adrenal hyperplasia due to 11-hydroxylase deficiency—Compound heterozygous mutations of a prevalent and two novel CYP11B1 mutations, Gene,626 (2017) 89–94
(8) Chongjuan Gu, Zhao Yang, Hao Tan, Yingying Zhang, Yilu Lu, and Yongxin Ma*, Decreased
Plasma COMP and Increased Plasma CTX-II Levels in a Chinese Pseudoachondroplasia Family with Novel COMP Mutation,BioMed Research International,Volume 2017, Article ID 5809787
(9) Chongjuan Gu, Hongxia Gong, Zheng Zhang, Zhao Yang and Yongxin Ma*, Association of interleukin-10 gene promoter polymorphisms with recurrent pregnancy loss: a meta-analysis. J Assist Reprod Genet (2016) 33:907–917
(10) 顾崇娟,张学红,《肿瘤生殖学》,兰州大学出版社,2013.