个人信息：
生秀杰，女，教授/主任医师，妇科主任兼妇科肿瘤专科主任，研究方向：妇科肿瘤
个人简介：毕业于中国医科大学，获得博士学位。毕业后曾在中国医科大学附属第一医院医院及广州医科大学附属第三医院工作。一直从事妇科临床、科研及教学工作，主要研究领域是妇科肿瘤。曾在美国University of Pittsburgh和Wayne State University做访问学者。擅长妇科良、恶性肿瘤的规范性诊治，子宫内膜异位症的综合处理，宫颈病变的规范管理，先天性生殖道畸形的矫治，盆腔脏器脱垂的处理以及妇科内分泌疾病的治疗；熟练开展妇科各级各类手术，包括传统开腹手术、阴式手术和宫、腹腔镜微创手术。
主持的主要研究课题：
1.卵巢癌中异常低表达的长链非编码RNA MEG3的靶基因及功能的研究，项目编号2013B021800307社会发展领域科技计划项目审批，立项金额：5万元
2.长链非编码RNA MALAT-1靶向调控STAT3信号通路促进卵巢癌侵袭、转移作用的机制研究,项目编号2014A020212517社会发展领域科技计划项目审批，立项金额：5万元
3.MALAT-1作为上皮性卵巢癌的新标志并促进卵巢癌侵袭转移,广州市科技计划项目项目编号20160701016920万
发表文章：以第一作者或通讯作者发表论文60余篇，副主编《妇科手术学》一部
1.Qirong Wen, MD,* Yan Liu, MD,* Huabing Lyu, MD,* Xiaying Xu, MD,* Qingxia Wu, MD,*Ni Liu, MD,* Qi Yin, MD,* Juan Li, MD,*T and Xiujie Sheng, MD, PhD*.Long Noncoding RNA GAS5, Which Acts as a Tumor Suppressor via microRNA 21, Regulates Cisplatin Resistance Expression in Cervical Cancer. International Journal of Gynecological Cancer,2017 Jul;27(6):1096-1108
2.Hongbiao Huang1,2†, Ni Liu1,2†, Yuning Liao2, Ningning Liu2,3, Jianyu Cai2, Xiaohong Xia2, Zhiqiang Guo2,Yanling Li2, Qirong Wen1, Qi Yin1, Yan Liu1, Qingxia Wu1, Dhivya Rajakumar2, Xiujie Sheng1* and Jinbao Liu2. Platinum-containing compound platinum pyrithione suppresses ovarian tumor proliferation through proteasome inhibition. Journal of Experimental & Clinical Cancer Research 2017 Jun 15;36(1):79
3.Yanqing Zhou, Xiaying Xu, Huabing Lv, Qirong Wen, Juan Li, Linyu Tan, Jianqi Li,Xiujie Sheng*. The Long Noncoding RNA MALAT-1 Is Highly Expressed in Ovarian Cancer and Induces Cell Growth and Migration. PLOS ONE ,PLoS One.2016 May 26;11(5)
4.Sheng X,Li J,Yang L,Chen Z,Zhao Q,Tan L,Zhou Y,Li JPromoter hypermethylation influences the suppressive role of maternally expressed 3, a long non-coding RNA, in the development of epithelial ovarian cancer.Oncol Rep.2014 Jul;32(1):277-85
5.Sheng xiujie*,Li zhen*,Sun man,Wang zhihui,Zhou dongmei,Li jianqi,Zhao qin,Sun xiaofangandLiu qicai. MACC1 induces metastasis in ovarian carcinoma by upregulating hepatocyte growth factor receptor c‑MET.ONCOLOGY LETTERS 2014(8): 891-897
