【个人简介】

  毛景松 广州医科大学附属清远医院介入血管外科  主任医师 医学博士 博士生导师  博士后联合培养导师 科室主任  

社会任职：中国医师协会介入医师介入医学工程与生物技术学组委员、广西省抗癌协会介入分会常务委员、 广西肿瘤疾病医疗质量控制中心肝癌质控专委会委员，广东省精准医学应用学会VTE分会副主任委员、广东省VTE血栓防治联盟临床专家委员会副主任委员。中华消化病与影像杂志（电子版）编委。第九届《中华肿瘤预防杂志》编委审稿人，BMJ case 审稿专家、《中华医学杂志》审稿专家、《肝博士》审稿专家、《现代肿瘤医学》青年编委、《中国CT与MR》青年编委、《中国影像医学杂志》青年编委、《Frontiers in Immunology》Top editor。

【研究方向】

长期从事介入医学及分子影像基础和临床研究工作，研究方向主要是人工智能（图像识别及介入手术机器人）、分子影像及肿瘤与血管疾病的相关研究

【科研项目】

1、2023 年国家自然基金地区项目 超稳定碘化油复合制剂介导 STING 协同增效的肝癌综合治疗 策略及机制研究 82360360 32 万 主持 (在研）

2、2023 年广西自治区中央引导性地方科技发展资金自由探索类基础研究类 肝细胞癌高特异性 多模态分子影像与人工智能辅助诊疗体系构建与机制研究 2023ZYZX1090 20 万 主持（结题）

3、2023年广西自治区自然科学基金面上项目 基于可视化精准引导下声动力增强免疫治疗肝肿瘤的基础研究 2022JJA141456  10万 主持（结题）

4、2022年福建省自然科学基金面上项目 基于绿色合成技术的新型碘化油栓塞复合制剂及其肝癌介入治疗机制研究 2022J01112991  10万 主持（结题）

5、2020年 厦门市内分泌肿瘤精准诊治重点实验室开放课题 仿生纯药分子探针在乳腺癌诊疗中的应用 5万主持 （已结题）

6、2019年 厦门市卫生健康系统科研立项 多功能栓塞微球协同微波治疗肝癌模型的应用研究 10万主持 (已结题）

【代表性论文及著作】

论文发表：第一作者/通讯作者（共同）

1.Lv Z, Yang J, Xu Y, Chen Y, Zhao L, Wang P, Dong X, Qin Y, Wang X, Xiao Q, Mao J*. Efficacy study of juxta-anastomotic stenosis of the arteriovenous fistula via percutaneous transluminal angioplasty with different accesses to the arteries and veins. Front Med (Lausanne). 2026 Jul 22;13:1883032. doi: 10.3389/fmed.2026.1883032. PMID: 42558985; PMCID: PMC13439415.

2.Peng Y, Liu H, Liang X, Cao L, Teng M, Chen H, Li Z, Peng X, Mao J*, Cheng H*, Liu G*. Self-assembling chemodrug fiber-hydrogel for transarterial chemoembolization and radiotherapy-enhanced antitumor immunity. J Control Release. 2025 Apr 10;380:1-16. doi: 10.1016/j.jconrel.2025.01.088. Epub 2025 Feb 3. PMID: 39892652.

3.Chen H, Xiong Y, Teng M, Li Y, Zhang D, Ren Y, Li Z, Liu H, Wen X, Li Z, Zhang Y, Askari Rizvi SF, Zhuang R, Huang J, Li S, Mao J*, Cheng H*, Liu G*. A preclinical and first-in-human study of superstable homogeneous radiolipiodol for revolutionizing interventional diagnosis and treatment of hepatocellular carcinoma. Acta Pharm Sin B. 2025 Oct;15(10):5022-5035. doi: 10.1016/j.apsb.2025.02.021. Epub 2025 Feb 21. PMID: 41132827; PMCID: PMC12541579.

4.Li Z, Mao J*. Cinematic Rendering of a Bronchial Artery Aneurysm. Radiology. 2025 Feb;314(2):e242488. doi: 10.1148/radiol.242488. PMID: 39998375.

5.Gao Chengtian#, Wang Mingdong#, Zheng Yali#, Zhang Liang, He Jiawei, Liu Bosen, Lin Xinhua, Mao Jingsong* and Wang Zhanxiang*. "Hepatotoxicity of nanomaterials: From mechanism to therapeutic strategy" Nanotechnology Reviews, vol. 13, no. 1, 2024, pp. 20240074.

6.Yang J#, Qin Y#, Lv Z#, Xiao Q, Miao Y, Huang H, Wei B*, Mao J*. Hepatic infarction occurred after 125I particle stent treatment for hepatocellular carcinoma with portal vein tumor thrombus: A case report. J Cancer Res Clin Oncol. 2024 Jun 17;150(6):308.(Q2 IF 3.6)

7.Yang Q#, Ye W#, Luo D#, Xing J, Xiao Q, Wu H, Yao Y, Wang G, Yang L, Guo D, Wang K, He Y, Ye X, Zhang J, Jin Z, Fan Z*, Wen X*, Mao J*, Chen X, Zhao Q*. Neuroprotective effects of anti-TRAIL-ICG nanoagent and its multimodal imaging evaluation in cerebral ischemia-reperfusion injury. Mater Today Bio. 2024 May 22;26:101094.(Q1 IF 8.2)

8.Wang J#, Xu J#, Mao J#, Fu S, Gu H, Wu N, Su G, Lin Z, Zhang K, Lin Y, Zhao Y, Liu G, Zhao H*, Zhao Q*. A novel hybrid machine learning model for auxiliary diagnosing myocardial ischemia. Front Cardiovasc Med. 2024 Feb 21;11:1327912.(Q2 IF 3.6)

9. Shuang Bai; Hu Chen; Shiying Fu; Chao Liu; Xing Gao; Shuo Li; Yulun Chen; Yulu Lan; Yutian Xia; Qixuan Dai; Pan He; Yang Zhang; Qingliang Zhao; Jingsong Mao*; Zhixiang Lu*; Gang Liu* ; Bioinspired Tumor Calcification‐Guided Early Diagnosis and Eradication of Hepatocellular Carcinoma, Advanced Materials, 2024, 2310818（Q1 IF 29）

10. Xiao Xu; Hu Chen; Zhenwen Zhao; Yangjie Wang; Pan He; Hongwei Cheng; Xing Gao; Yesi Shi; Yesen Li; Jinxiong Huang; Yisheng Peng; Chengchao Chu; Yang Zhang; Chao Liu; Bo Li; Jingsong Mao*; Hongjuan Ma*; Gang Liu* ; Engineering Radioactive Microspheres for Intra‐Arterial Brachytherapy Using Radiation‐Induced Graft Polymerization, Advanced Functional Materials, 2023, 33(50): 2306215（Q1 IF 19.00）

11.Peng Lv#, Hu Chen#,Hongwei Cheng, Xuan Liu, Chao Liu, Yun Zeng, Lai Jiang, Xiaoyong Wang, Jingsong Mao*, and Gang Liu *.A calcium alginate hydrogel microsphere-based transcatheter arterial viroembolization strategy for hepatocellular carcinoma. Advanced Therapeutics.2023, 2200174. https://doi.org/10.1002/adtp.202200174 （Q2 IF 5.003）

12.Mu X, Huang X, Jiang Z, Li M, Jia L, Lv Z, Fu W*, Mao J*. [18F]FAPI-42 PET/CT in differentiated thyroid cancer: diagnostic performance, uptake values, and comparison with 2-[18F]FDG PET/CT. Eur J Nucl Med Mol Imaging. 2022 Dec 10. doi: 10.1007/s00259-022-06067-2 (中科院1区 10.056)

13.Pan He#, En Ren#, Biaoqi Chen#, Hu Chen#, Hongwei Cheng, Xing Gao, Xiaoliu Liang,HaoLiu, Jingdong Li, Bo Li, Aizheng Chen, Chengchao Chu, Xiaoyuan Chen, Jingsong Mao*, Yang Zhang*, Gang Liu*.A super-stable homogeneous lipiodol-hydrophilic chemodrug formulation for treatment of hepatocellular carcinoma.Theranostics 2022; doi:10.7150/thno.68456（中科院 1区 IF 11.556)

14.Linhai Yang#, Yulun Chen#, Jing Wang, Shuting Ling, Guangxing Wang, Bei Zhang, Hengyu Zhao*, Qingliang Zhao*, Jingsong Mao*.  Research progress on the application of optical coherence tomography in the field of oncology. Front. Oncol.2022 Jul 25;12:953934. (IF 5.738).

15.Zhenjie Li#,Hongwei Chen#,Jingsong Mao*,Gang Liu*.Conversion Therapy of Intermediate and Advanced Hepatocellular Carcinoma Using Superstable Homogeneous Iodinated Formulation Technology. SCIENCE CHINA Life Sciences.2022 Aug 26. (IF 10.372)

16.Xiaoyi Hu,  Jiwei Li,Yulun Chen,  Qiuyue Long,Yangyuyan Bai,  Ran Li,Keqiang Wang, Mingzheng Jiang,  Chaoyang Chen, Jingsong Mao, *Yali Zheng, * and Zhancheng Gao *A Self-assembly ICG Nanoparticle Potentiating Targeted Photothermal and Photodynamic Therapy in NSCLC.ACS Biomaterials Science & Engineering 2022 Sep 7. doi: 10.1021/acsbiomaterials.2c00620.（IF 5.395）

17、Huang D#, Wang G#, Mao J#, Liu C#, Fan Z, Zhang Y, Zhang B, Zhao Y, Dai C, He Y, Ma H, Liu G, Chen X, Zhao Q. Intravital Whole-Process Monitoring Thermo-Chemotherapy Via 2D Silicon Nanoplatform: A Macro Guidance and Long-Term Microscopic Precise Imaging Strategy. Adv Sci (Weinh). 2021 Aug;8(16):e2101242. doi: 10.1002/advs.202101242. Epub 2021 Jun 24. PMID: 34166580; PMCID: PMC8373095.(中科院1区  IF 16.806)

18、Tianhong Yao#, Huirong Lin#, Jingsong Mao*, Shuaidong Huo* and Gang Liu*. CT Imaging Features of Patients Infected with 2019 Novel Coronavirus.BIO Integration,  5 April 2021, 1(2）pp. 5-11(7).DOI: https://doi.org/10.15212/bioi-2020-0038.(无分值）

19、He P*, Guan S*, Ren E, Chen H, Chen H, Peng Y, Luo B, Xiong Y, Li B*, Li J*, Mao J*, Liu G*. Precision Interventional Brachytherapy: A Promising Strategy Toward Treatment of Malignant Tumors. Front Oncol. 2021 Oct 8;11:753286. doi: 10.3389/fonc.2021.753286. PMID: 34692537; PMCID: PMC8531520.（中科院2区 IF 6.244)

20、Yonghe Jiang#, Yang Zhang#, Zhixiang Lu#, Xiaoyong Wang, Shuang Bai,Yulun Chen,

Jingsong Mao*,Gang Liu*.Liquid Embolic Agents for Interventional Embolization.ChemPhysMater.https://doi.org/10.1016/j.chphma.2021.09.008.(无分值）

21、Lin H,Zhou Y,Wang J,Wang H,Yao T,Chen H, Zheng H,Zhang Y,Ren E,Jiang  L,Chu C,Chen X,Mao J*,Wang F*,Liu G*.Repurposing ICG enables MR/PA imaging signal amplification and iron depletion for iron-overload disorders.Science Advances. 2021 Dec 17;7(51):eabl5862. doi: 10.1126/sciadv.abl5862. Epub 2021 Dec 17. PMID: 34919434; PMCID: PMC8682994.（中科院1区 14.143)

22、Yang Zhang #, Hongwei Cheng #, Hu Chen#, Peiyao Xu #, En Ren a, Yonghe Jiang a, Dengfeng Li a, Xing Gao a, Yating Zheng a, Pan He a, Huirong Lin a, Biaoqi Chen c, Gan Lin a, Aizheng Chen c, Chengchao Chu*, Jingsong Mao* ,Gang Liu*.A pure nanoICG-based homogeneous lipiodol formulation: Toward precise surgical navigation of primary liver cancer after long-term transcatheter arterial embolization.European Journal of Nuclear Medicine and Molecular Imaging. 2021 Dec 23. doi: 10.1007/s00259-021-05654-z. Epub ahead of print. PMID: 34939176.(中科院1区 IF 9.236)

23、Chen H#, Cheng H#, Dai Q#, Cheng Y#, Zhang Y, Li D, Sun Y, Mao J*, Ren K, Chu C*, Liu G*. A superstable homogeneous lipiodol-ICG formulation for locoregional hepatocellular carcinoma treatment. J Control Release. 2020 Jul 10;323:635-643. doi: 10.1016/j.jconrel.2020.04.021. Epub 2020 Apr 14. PMID: 32302761.(中科院1区 IF 9.776)

24、Hu Chen#, Hongwei Cheng#, Wenying Wu#, Dengfeng Li, Jingsong Mao*, Chengchao Chu*, and Gang Liu*. The blooming intersection of transcatheter hepatic artery chemoembolization and nanomedicine. Chinese Chemical Letters. 2020, 31(6):1375-1381.(中科院2区 IF 6.779)

25、Mao J#, Tang S#, Hong D, Zhao F, Niu M, Han X, Qi J, Bao H, Jiang Y, Fu C, Long D, Meng X*, Su H*. Therapeutic efficacy of novel microwave-sensitized mPEG-PLGA@ZrO2@(DOX + ILS) drug-loaded microspheres in rabbit VX2 liver tumours. Nanoscale. 2017 Mar 9;9(10):3429-3439. doi: 10.1039/c6nr09862b. PMID: 28233003.(中科院2区 IF 7.79)

参编樊代明院士《整合肿瘤学-基础篇》、《核医学诊疗病例精解第一版》副主编。

【所获荣誉和奖励】

1、2022 年福建省医学科技厅二等奖

肿瘤诊疗一体化分子影像探针设计、构建及临床应用研究 （第五完成人）

2、2024年中国医药教育协会科学技术创新二等奖。

肝细胞癌特异性多模态分子影像与人工智能辅助诊疗体系的构建与机制研究（第二完成人）