研究生院

贺超
更新时间:2024-11-05


贺超,广州医科大学附属第三医院骨科教授,广州市卫健委优秀人才,广州市健康科普专家,广州医科大学“南山学者”,硕士生导师,博后合作导师。研究方向:骨肿瘤的诊疗及机制探究,重点研究3D打印支架用于骨肉瘤的治疗与骨修复。研究涉及纳米生物材料、3D打印、组织工程、肿瘤的表观遗传调控和分子生物学机制。以通讯/第一作者共发表SCI论文12篇(IF>10分的7篇),包括Nano Today、Advanced Functional Materials(2)、Advanced Science、Biomaterials(2)Small、Cell Death & Disease、Clinical Epigenetics等。授权发明专利5项,授权实用新型专利5项。担任《Exploration》、《Nano Materials Science》(IF: 12.6)青年编委。担任中国中医药信息学会中西医外科智能诊疗分会理事。


学习经历:

2012.09-2017.06 上海交通大学医学院 临床医学(五年制) 本科

2017.09-2022.06 上海交通大学医学院 外科学(骨外科) 博士 导师:郝永强


工作经历:

2022.08-至今 广州医科大学附属第三医院教授


已发表SCI文章:#共同一作,*共同通讯

[1] Yuanhui Li#, Jian Li#, Yuxuan Zhong#, Qingshun Zhang#, Yuchun Wu, Jinpeng Huang, Kaicheng Pang, Yuanyue Zhou, Tong Xiao, Zenghui Wu*, Wei Sun*, Chao He*. pH-Responsive and Nanoenzyme-Loaded Artificial Nanocells Relieved Osteomyelitis Efficiently by Synergistic Chemodynamic and Cuproptosis Therapy. Biomaterials. 2025, 313, 122762. (IF12.8, Q1)

[2] Chao He*, Yuhang Jiang, Yuan Guo, Zenghui Wu*. Amplified Ferroptosis and Apoptosis Facilitated by Differentiation Therapy Efficiently Suppress the Progression of Osteosarcoma. Small. 2023, 19(44): 2302575. (IF13.0, Q1)

[3] Chao He#, Caihong Dong#, Hui Hu, Luodan Yu*, Yu Chen*, Yongqiang Hao*. Photosynthetic Oxygen-Self-Generated 3D-Printing Microbial Scaffold Enhances Osteosarcoma Elimination and Prompts Bone Regeneration. Nano Today. 2021, 41: 101297. (IF13.2, Q1)

[4] Chao He, Luodan Yu*, Heliang Yao, Yu Chen*, Yongqiang Hao*. Combinatorial Photothermal 3D-Printing Scaffold and Checkpoint Blockade Inhibits Growth/Metastasis of Breast Cancer to Bone and Accelerates Osteogenesis. Advanced Functional Materials. 2021, 31(10): 2006214. (IF18.5, Q1)

[5] Chao He#, Caihong Dong#, Luodan Yu*, Yu Chen*, Yongqiang Hao*. Ultrathin 2D Inorganic Ancient Pigment Decorated 3D-Printing Scaffold Enables Photonic Hyperthermia of Osteosarcoma in NIR-II Biowindow and Concurrently Augments Bone Regeneration. Advanced Science. 2021, 8(19): 2101739. (IF14.3, Q1)

[6] Chao He, Luodan Yu*, Li Ding, Yu Chen*, Yongqiang Hao*. Self-Assembled/Drug-Composed Nanomedicine for Synergistic Photonic Hyperthermia and Targeted Therapy of Breast Cancer by Inhibiting ERK, AKT, and STAT3 Signaling Cascades. Advanced Functional Materials. 2020, 30(10): 1908907. (IF18.5, Q1)

[7] Chao He, Luodan Yu*, Li Ding, Heliang Yao, Yu Chen*, Yongqiang Hao*. Lysine Demethylase KDM3A Regulates Nanophotonic Hyperthermia Resistance Generated by 2D Silicene in Breast Cancer. Biomaterials. 2020, 255: 120181. (IF12.8, Q1)

[8] Chao He#, Chao Liu#, Lei Wang, Yangbai Sun*, Yuhang Jiang*, Yongqiang Hao*. Histone Methyltransferase NSD2 Regulates Apoptosis and Chemosensitivity in Osteosarcoma. Cell Death & Disease. 2019, 10(2): 65. (IF8.1, Q1)

[9] Chao He#, Jian Sun#, Chao Liu*, Yuhang Jiang*, Yongqiang Hao*. Elevated H3K27me3 Levels Sensitize Osteosarcoma to Cisplatin. Clinical Epigenetics. 2019, 11(1): 8. (IF4.8, Q1)

[10] Chao He, Tingting Wu*, Yongqiang Hao*. Anlotinib Induces Hepatocellular Carcinoma Apoptosis and Inhibits Proliferation via Erk and Akt Pathway. Biochemical and Biophysical Research Communications. 2018, 503(4): 3093–3099. (IF2.5, Q3)

[11] Chao He#, Zhenyu Sun#, Robert M. Hoffman, Zhijian Yang, Yuhang Jiang*, Lei Wang*, Yongqiang Hao*. P-Glycoprotein Overexpression is Associated with Cisplatin Resistance in Human Osteosarcoma. Anticancer Research. 2019, 39(4): 1711–1718. (IF1.6, Q4)

[12] Chaoyin Jiang#, Chao He#, Zhiqiang Wu#, Fengfeng Li#,*, Jianru Xiao*. Histone Methyltransferase SETD2 Regulates Osteosarcoma Cell Growth and Chemosensitivity by Suppressing Wnt/β-catenin Signaling. Biochemical and Biophysical Research Communications. 2018, 502(3): 382–388. (IF2.5, Q3)


已授权专利:

[1] 贺超,吴增晖:一种治疗骨肉瘤的复合物及其制备方法,2023-09-26,中国,ZL 2022 1 1172122.X(发明专利)

[2] 贺超,郝永强,王磊:生物3D打印植入凝胶及其在软组织缺损修复中的应用,2021-06-29,中国,ZL 2019 1 0607789.X(发明专利)

[3] 郝永强,贺超:用于软组织腔性缺损修复的可降解功能性植入囊状体,2020-07-24,中国,ZL 2019 2 1042248.9(实用新型专利)

[4] 郝永强,符静珂,贺超:一种pH响应性释放氧气和活性氧的氧化硅纳米反应器及其制备方法,2021-05-18,中国,ZL 2018 1 1082335.7发明专利)

[5] 郝永强,符静珂,贺超:一种放疗增敏纳米材料的用途,2021-01-29,中国,ZL 2018 1 1082334.2发明专利)

[6] 符静珂,郝永强,姜闻博,富灵杰,贺超,马思聪:一种温度响应性缓释氧气的纳米复合材料及其制备方法和应用,2021-06-29,中国,ZL 2018 1 1452428.4发明专利)


杂志任职:

Nano Materials Science》青年编委

Exploration》青年编委


科研项目:

1. 国家自然科学基金青年项目,膜靶向脂质体通过诱导分化和铁死亡抑制骨肉瘤的疗效及机制研究,编号:32301166,项目负责人,30万,2024年01月至2026年12月

2. 广州医科大学,南山学者科研启动经费,项目负责人,230万,2022年08月至2027年08

 
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