【个人简介】

张霄旦

医学博士，毕业于中山大学临床医学（八年制），中山大学优秀毕业生；

广州市卫生健康委优秀人才；

现为广州医科大学附属第二医院内分泌科副主任医师，任广州医科大学硕士研究生导师、“创新班”导师、本科生导师；

现任广东省医学会糖尿病学分会青年委员，广东省医院协会糖尿病管理专业委员会委员，广东省临床医学学会糖尿病教育与支持分会青年委员；

担任《Diabetes, Obesity and Metabolism》、《Scientific reports》等SCI杂志的审稿人。

【研究方向】

糖尿病心肌病等糖尿病慢性并发症

【科研项目】

主持国家自然科学基金、广东省自然科学基金、广州市科技计划等国家级及省市级科研项目多项，目前在研经费45万元。

【代表性论文及著作】

已以第一作者及通讯作者发表SCI论文十余篇（总影响因子50+）及中文核心期刊论文十余篇。代表性论文列举如下：

1.Zhang X, Yan D, Du T, Zhao Y, Zhang J, Zhang T, Lin M, Li Y, Li W. Efficacy and safety of basal-bolus insulin at 1:1.5 ratio compared to 1:1 ratio using a weight-based initiation and titration (WIT2) algorithm in hospitalized patients with type 2 Diabetes: a multicenter, randomized, clinical study. Diabetol Metab Syndr, 2023, 15(1): 243.

2.Zhang X, Luo Z, Li J, Lin Y, Li Y, Li W. Sestrin2 in diabetes and diabetic complications. Front Endocrinol, 2023, 14: 1274686.

3.Deng X, Yi M, Li W, Ye H, Chen Z, Zhang X (Corresponding author). The prevalence, hospitalization outcomes and risk factors of euthyroid sick syndrome in patients with diabetic ketosis/ketoacidosis. BMC Endocr Disord, 2023, 23(1): 195.

4.Zhang X, Chen Y, Ye H, Luo Z, Li J, Chen Z, Zhang E, Li W. Correlation between thyroid function, sensitivity to thyroid hormones and metabolic dysfunction-associated fatty liver disease in euthyroid subjects with newly diagnosed type 2 diabetes. Endocrine, 2023, 80(2): 366-379.

5.Li Y, Yi M, Deng X, Li W, Chen Y, Zhang X (Corresponding author). Evaluation of the Thyroid Characteristics and Correlated Factors in Hospitalized Patients with Newly Diagnosed Type 2 Diabetes. Diabetes Metab Syndr Obes, 2022, 15: 873-884.

6.Zhang X, Deng X, Ye H, Chen Z, Li W. Inhibition of Sestrin2 overexpression in diabetic cardiomyopathy ameliorates cardiac injury via restoration of mitochondrial function. Exp Ther Med, 2022, 23(4): 265.

7.Zhang X, Deng X, Zhou J, Qiu K, Deng M, Lin Z, Mosha S, Li W. The association of serum cortisol level with microalbuminuria in patients with type 2 diabetes and prediabetes. Int J Med Sci, 2020, 17(18): 2998-3004.

8.Zhang X, Zhang T, Xiang G, Wang W, Li Y, Du T, Zhao Y, Mosha S, Li W. Comparison of weight-based insulin titration (WIT) and glucose-based insulin titration using basal-bolus algorithm in hospitalized patients with type 2 diabetes: a multicenter, randomized, clinical study. BMJ Open Diabetes Res Care, 2020, 8(1): e001261.

9.Zhang X, Zhong Z, Li Y, Li W. Long-term renal outcomes associated with sodium glucose cotransporter 2 inhibitors in patients with type 2 diabetes mellitus: A systematic review and meta-analysis. Diabetes Metab Res Rev, 2020, 36(5): e3303.

10.Zhang X, Zhong Z, Li W. Downregulation of TRAP1 aggravates injury of H9c2 cardiomyocytes in a hyperglycemic state. Exp Ther Med, 2019, 18(4): 2681-2686.

11.Zhang X, Zhao Q. Effects of dipeptidyl peptidase-4 inhibitors on blood pressure in patients with type 2 diabetes: A systematic review and meta-analysis. J Hypertens, 2016, 34(2): 167-175.

12.Zhang X, Zhao Q. Association of thiazide-type diuretics with glycemic changes in hypertensive patients: a systematic review and meta-analysis of randomized controlled clinical trials. J Clin Hypertens (Greenwich), 2016, 18(4): 342-351.

13.Zhang X, Zhao J, Zhao T, Liu H. Effects of intensive glycemic control in ocular complications in patients with type 2 diabetes: a meta-analysis of randomized clinical trials. Endocrine, 2015, 49(1): 78-89.

14.Zhao Q, Zhang X (Co-first Author), Fang Y, Gong J, Gu B, Ma G. Current situation and associated factors of withdrawing or withholding life support to patients in an intensive care unit of cancer center in China. PLoS ONE, 2014, 9(5): e98545.

15.Zhang X, Zhao Q, Chen G, Zhang H, Zhang W, Yang X. Perioperative comprehensive supportive care interventions for Chinese patients with esophageal carcinoma: a prospective study. Asian Pac J Cancer Prev, 2013, 14(12): 7359-7366.

【所获荣誉和奖励】

1.2023年荣获“广州市卫生健康委优秀人才”;

2.2020年获广州医科大学第二临床学院“优秀教师”；

3.2017年获广州医科大学“优秀兼职班主任”。