
【个人简介】
广州医科大学呼吸疾病全国重点实验室PI,广东省珠江学者,广州医科大学南山学者。于2021年获得荷兰格罗宁根大学博士学位,随后分别在荷兰格罗宁根大学和帝国理工学院国家心肺研究所进行博士后研究。
【研究方向】
慢阻肺以及肺动脉高压的发病机制研究和基于靶点的药物研发。研究方法主要包括利用多组学技术发现疾病关键生物标志物,并结合多种肺类器官模型探索肺的损伤和修复机制。
【科研项目】
1. 国家自然科学基金青年项目, 2027-01-01至2029-12-31,30万,在研,主持。
2. 呼吸疾病全国重点实验室自主课题,2026-09-01至2029-08-31,20万,在研,主持。
3. 广州国家实验室-广州医科大学呼吸疾病全国重点实验室联合项目,300万,在研,主要参与人。
【代表性论文及著作】
1.Song. S., van Dijk. F., van Eck, G.W.A, ... & Melgert, B. N., Inhalable textile microplastic fibers impair airway epithelial differentiation. Am J Respir Crit Care Med. 2024 Feb 15;209(4):427- 443. ( IF=19.4,一区)
2.Song, S., Xiao, Z., Dekker, F. J., ... &Melgert, B. N., Macrophage migration inhibitory factor family proteins are multitasking cytokines in tissue injury. Cell Mol Life Sci.2022, 79, 105. (IF=6.2, 一区)
3.Song, S., Liu, B., Habibie, H., ... & Melgert, B. N., D-dopachrome tautomerase contributes to lung epithelial repair via atypical chemokine receptor 3-dependent Akt signaling. EBioMedicine. 2021, 68, 103412.(IF=10.8,一区)
4.Song, S., Huang, B., Wang, Q., ... & Wei, W., BF02, a recombinant TNFR2 fusion protein, alleviates adjuvant arthritis by regulating T lymphocytes in rats. Acta Pharmacologica Sinica 2013, 34, 414. (IF=8.4 ,一区)
5.Xiao, Z.*, Song, S.*, Chen, D., ... & Dekker, F. J., Proteolysis Targeting Chimera (PROTAC) for Macrophage Migration Inhibitory Factor (MIF) Has Anti-Proliferative Activity in Lung Cancer Cells. Angew Chem Int Ed Engl. 2021, 60, 17514. (*共同一作,IF=16.9, 一区)
6.Boucly A, Song S, … & Kivimaki M, Rhodes CJ, Wilkins MR. Clustering Patients with Pulmonary Hypertension Using the Plasma Proteome. Am J Respir Crit Care Med. 2025 Aug;211(8):1492-1503. ( IF=19.4,一区)
7.Mulas, F., Wang, X., Song, S., Nishanth, G., ... & Schlüter, D., The deubiquitinase OTUB1 augments NF-κB-dependent immune responses in dendritic cells in infection and inflammation by stabilizing UBC13. Cell Mol Immunol. 2021 Jun;18(6):1512-1527.(IF=22.096 一区)