【个人简介】
王伟，博士，呼吸疾病全国重点实验室PI，南山学者特聘教授，博士生导师。国家自然科学基金优秀青年科学基金项目（海外）获得者，广东省教育厅“珠江人才计划”青年学者。广东省预防医学会过敏疾病预防与控制专业委员会常务委员和广东省呼吸与健康学会嗜酸粒细胞增多相关性肺疾病专业委员会委员。Comparative Immunology, Microbiology & Infectious Diseases和Infectious Medicine期刊的编委。2015年在北京协和医学院获得博士学位。随后前往哈佛医学院进行博士后培训，2022年晋升为讲师。2024年全职加入呼吸疾病全国重点实验室。共发表SCI论文18篇，引用超过1200次。其中第一作者和通讯作者7篇，包括Immunity， Journal of Allergy and Clinical Immunology，Cell Research和EBioMedicine等。获得国家授权专利2项。
【研究方向】
王伟博士通过“干湿结合”的模式，长期从事哮喘和慢阻肺等慢性呼吸疾病的免疫学和组学研究，研究方向包括：
1.儿童过敏性哮喘中神经免疫调节机制；
2.多组学分析鉴定儿童过敏性哮喘激素耐受机制和药物新靶点；
3.CRISPR筛选哮喘和肺感染中组织定居记忆性T细胞关键调控因子；
4.靶向组织定居记忆性T细胞关键调控因子小分子药物筛选。
【科研项目】
1.国家自然科学基金优秀青年科学基金项目（海外）, 组织定居记忆性Th2细胞与过敏性哮喘，2025-01-01至2027-12-31，主持。
【代表性论文及著作】
1. Kamakshi Bankoti*, Wei Wang*, Gaurang M. Amonkar, Linjie Xiong, Jessica E. Shui, Mwase Chimwemve, Jin-Ah Park, Hongmei Mou, Yinshan Fang, Jianwen Que, Yan Bai, Paul H. Lerou and Xingbin Ai. Airway basal stem cells in COVID-19 exhibit a proinflammatory signature and impaired mucocililary differentiation. American Journal of Respiratory Cell and Molecular Biology. 2024 Jan;70(1):26-38.
2. Jianye Deng*, Hong-Jin Zhao*, Ying Zhong*, Cuiping Hu, Shiqin Zhu, Jinlai Meng, Chunling Wang, Xiangxin Lan, Xiyao Wang, Zi-Jiang Chen, Junhao Yan†, Wei Wang†, Yan Li†. H3K27me3-regulated Human Trophoblast BMP2 Signaling Enhancement Can Alleviate Shallow Trophoblast Invasion in Preeclampsia. eBioMedicine. 2023 Jun 16;93:104664.
3. Wei Wang*†, Carolyn Garcia, Fengzhi Shao, Jonathan A. Cohen, Yan Bai, Alan Fine and Xingbin Ai. Lung dopaminergic nerves facilitate the establishment of TH2 resident memory cells in early life. Journal of Allergy and Clinical Immunology. 2023 Aug 3;152(23):386-99.
4. Wei Wang*, Jonathan A. Cohen, Antonia Wallrapp, Kenneth G. Trieu, Juliana Barrios, Fengzhi Shao, Nandini Krishnamoorthy, Vijay K. Kuchroo, Matthew R. Jones, Alan Fine, Yan Bai, Xingbin Ai. Age-related dopaminergic innervation augments T helper 2-type allergic inflammation in the postnatal lung. IMMUNITY. 2019 Dec 17;51(6):1102-1118.e7.
5. Wei Wang*†, Xingbin Ai. Primary culture of immature, naïve mouse CD4+ T cells. STAR Protocols. 2021 Aug 14;2(3):100756.
6. Wei Wang*, Penghui Yang*, Ying Zhong*, Zhongpeng Zhao, Li Xing, Yan Zhao, Zhen Zou, Yanli Zhang, Chenggang Li, Taisheng Li, Chen Wang, Zhong Wang, Xuezhong Yu, Bin Cao, Xiang Gao, Josef M. Penninger, Xiliang Wang and Chengyu Jiang. Monoclonal antibody against CXCL-10/IP-10 ameliorates influenza A (H1N1) virus induced acute lung injury. Cell Research. 2013 Apr;23(4):577-80.
7. JingGuo*, Fengming Huang*, Jun Liu*, Yu Chen*, Wei Wang*, Bin Cao*, Zhen Zou, Song Liu, Jingcao Pan, Changjun Bao, Mei Zeng, Haixia Xiao, Hainv Gao, Shigui Yang, Qiang Liu, Huandi Zhou, Jingdong Zhu, Xiaoli Liu, Weifeng Liang, Yida Yang, Shufa Zheng, Jiezuan Yang, Hongyan Diao, Kunkai Su, Li Shao, Hongcui Cao, Ying Wu, Min Zhao, Shuguang Tan, Hui Li, Xiaoqing Xu, Chunmei Wang, Jianmin Zhang, Li Wang, Jianwei Wang, Jun Xu, Dangsheng Li, Nanshan Zhong, Xuetao Cao, George F. Gao, Lanjuan Li and Chengyu Jiang. The Serum Profile of Hypercytokinemia Factors Identified in H7N9-Infected Patients can Predict Fatal Outcomes. Scientific Reports. 2015 Jun 1;5:10942.
完整的已发表论文：https://www.ncbi.nlm.nih.gov/myncbi/wei.wang.38/bibliography/public/
【所获荣誉和奖励】
1.2024年荣获广东省教育厅“珠江人才计划”青年学者;
【联系方式】
wangwei0429@gmail.com
